Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.63 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 2/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668652 | 0.84 | HRH3 (0.58) | HRH3NOTUMCHRM4DGAT2CCNC | |
| SCHEMBL4668384 | 0.82 | HRH3 (0.90) | HRH3NOTUMCHRM4DGAT2 | |
| SCHEMBL4668383 | 0.82 | HRH3 (0.90) | HRH3NOTUMCHRM4DGAT2 | |
| SCHEMBL4667344 | 0.82 | HRH3 (0.90) | HRH3NOTUMCHRM4DGAT2 | |
| Hydrochloric Acid SCHEMBL4669579 | 0.82 | HRH3 (0.89) | HRH3NOTUMCHRM4DGAT2 | |
| Hydrochloric Acid SCHEMBL4669578 | 0.82 | HRH3 (0.89) | HRH3NOTUMCHRM4DGAT2 | |
| Hydrochloric Acid SCHEMBL4666741 | 0.82 | HRH3 (0.89) | HRH3NOTUMCHRM4DGAT2 | |
| SCHEMBL4668375 | 0.81 | HRH3 (0.63) | HRH3NOTUMCHRM4DGAT2CCNC | |
| SCHEMBL4666663 | 0.81 | HRH3 (0.66) | HRH3NOTUMCHRM4DGAT2CCNC | |
| SCHEMBL4666684 | 0.81 | HRH3 (0.63) | HRH3NOTUMCHRM4DGAT2CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802307-B1 | PYRROLIDINE DERIVATIVES AS HISTAMINE RECEPTORS LIGANDS | GLAXO GROUP LTD (GB) | 2008-02-27 | — | — | EP | claimed |