SCHEMBL4670905

SCHEMBL4670905

CNN(C)C(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1OC

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 7/20 0.55
CNR1 P21554 5/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL969917 0.86 CNR2 (0.58) CNR2CNR1
SCHEMBL971303 0.84 CNR2 (0.58) CNR2CNR1
Hydrochloric Acid SCHEMBL8012747 0.82 CNR1 (0.55) CNR2CNR1
SCHEMBL970060 0.77 CNR1 (0.64) CNR2CNR1
SCHEMBL972417 0.77 CNR1 (0.77) CNR2CNR1
SCHEMBL3181790 0.76 CNR1 (0.67) CNR2CNR1
SCHEMBL3185493 0.76 CNR2 (0.70) CNR2CNR1
SCHEMBL970896 0.76 CNR1 (0.64) CNR2CNR1
SCHEMBL974370 0.76 CNR2 (0.78) CNR2CNR1
SCHEMBL908804 0.75 CNR2 (0.52) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1951678-A1 PYRAZOLE COMPOUNDS HAVING CANNABINOID RECEPTOR (CB1) ANTAGONIZING ACTIVITY Mitsubishi Tanabe Pharma Corporation (JP) 2008-08-06 EP disclosed
WO-2007046550-A1 PYRAZOLE COMPOUNDS HAVING CANNABINOID RECEPTOR (CB1) ANTAGONIZING ACTIVITY MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-04-26 WO disclosed