SCHEMBL4670993

SCHEMBL4670993

C=CC(=O)CCCOP(=O)(O)O

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 9/20 0.53
LPAR2 Q9HBW0 7/20 0.53
LPAR1 Q92633 5/20 0.44
ENPP2 Q13822 1/20 0.38
TPI1 P60174 1/20 0.36
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.33
CYP3A4 P08684 1/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
CSNK2A1 P68400 1/20 0.33
CSNK2A3 Q8NEV1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7621893 0.94 LPAR3 (0.56) LPAR3LPAR2LPAR1ENPP2TPI1
SCHEMBL29804741 0.92 LPAR3 (0.59) LPAR3LPAR2LPAR1ENPP2TPI1
SCHEMBL7624680 0.92 LPAR3 (0.59) LPAR3LPAR2LPAR1ENPP2TPI1
SCHEMBL7621154 0.92 LPAR3 (0.59) LPAR3LPAR2LPAR1ENPP2TPI1
SCHEMBL29870530 0.92 LPAR3 (0.59) LPAR3LPAR2LPAR1ENPP2TPI1
SCHEMBL2140462 0.88 LPAR3 (0.52) LPAR3LPAR2LPAR1ENPP2TPI1
SCHEMBL28330673 0.80 LPAR3 (0.42) LPAR3LPAR2LPAR1ENPP2
SCHEMBL29809912 0.79 BTN3A1 (0.47) LPAR3LPAR2LPAR1ALDH1A1TSHR
SCHEMBL4796221 0.77 LPAR3 (0.46) LPAR3LPAR2LPAR1ENPP2TPI1
SCHEMBL12304888 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1541333-A1 Scratch resistant moisture-protecting parylene layers Agfa-Gevaert (BE) 2005-06-15 EP claimed
US-20050067584-A1 Scratch resistant moisture-protecting parylene layers AGFA NV (BE) 2005-03-31 US claimed
EP-1998338-A1 Needle image plate or panel suitable for use in CR or DR imaging. Agfa HealthCare NV (BE) 2008-12-03 EP disclosed
US-7193226-B2 Scratch resistant moisture-protecting parylene layers AGFA-GEVAERT (BE) 2007-03-20 US disclosed
EP-1541333-A1 Scratch resistant moisture-protecting parylene layers Agfa-Gevaert (BE) 2005-06-15 EP disclosed
US-20050067584-A1 Scratch resistant moisture-protecting parylene layers AGFA NV (BE) 2005-03-31 US disclosed
EP-0844006-B1 Liquid-absorbing material composition, molded product therefrom, process for preparing the same and use thereof SHOWA DENKO KK (JP) 2002-06-05 EP disclosed
US-5965651-A CONTAINING A CROSSLINKING AGENT, N-VINYLCARBOXAMIDE COPOLYMER HAVING A FUNCTIONAL GROUP CAPABLE OF CROSSLINKING WITH CROSSLINKER, WATER, WATER SOLUBLE ORGANIC SOLVENT, AND PLASTICIZER; MOLDED INTO FILMS, SHEETS, POWDER AND FLAKES SHOWA DENKO K.K. (JP) 1999-10-12 US disclosed
EP-0844006-A1 Liquid-absorbing material composition, molded product therefrom, process for preparing the same and use thereof SHOWA DENKO KABUSHIKI KAISHA (JP) 1998-05-27 EP disclosed
EP-0446636-B1 External application base or auxiliary agent and external application composition for human being or animal containing the same SHOWA DENKO KK (JP) 1996-06-12 EP disclosed
US-5455042-A Ointment comprising a homogenous mixture of a polymer or copolymer of N-vinylacetamide, water and/or alcohols, and a pharmacologically active component SHOWA DENKO KABUSHIKI KAISHA (JP) 1995-10-03 US disclosed
US-5344655-A Drug delivery SHOWA DENKO K.K. (JP) 1994-09-06 US disclosed
US-5254338-A N-vinylacetamide polymer SHOWA DENKO K.K. (JP) 1993-10-19 US disclosed
EP-0446636-A2 External application base or auxiliary agent and external application composition for human being or animal containing the same SHOWA DENKO KABUSHIKI KAISHA (JP) 1991-09-18 EP disclosed
EP-0226193-B1 PROCESS FOR THE ADHESION OF POLY-P-XYLYLENE TO SUBSTRATES AND MANUFACTURED ARTICLES Montedison S.p.A. (IT) 1990-09-12 EP disclosed
US-4784881-A Process for the adhesion of poly-p-xylylene to substrates by means of phosphoric acid ester primers MONTEDISON S.P.A (IT) 1988-11-15 US disclosed
EP-0226193-A1 Process for the adhesion of poly-P-xylylene to substrates and manufactured articles Montedison S.p.A. (IT) 1987-06-24 EP disclosed