SCHEMBL467293

SCHEMBL467293

C=CC(Cc1ccccc1)c1c(C(=O)O)ccc(C(=O)O)c1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.39
MME P08473 1/20 0.37
ALPI P09923 1/20 0.37
PKM P14618 1/20 0.37
PTGS1 P23219 1/20 0.37
XIAP P98170 1/20 0.37
SLC7A5 Q01650 1/20 0.37
CPA3 P15088 3/20 0.36
EPHX1 P07099 2/20 0.36
MDM2 Q00987 1/20 0.36
DHODH Q02127 1/20 0.35
CPA1 P15085 2/20 0.35
FOLH1 Q04609 1/20 0.35
CPB1 P15086 1/20 0.35
CPB2 Q96IY4 1/20 0.35
CAPN1 P07384 1/20 0.35
SRR Q9GZT4 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4591556 0.81 CYP1A2 (0.38) CYP1A2MMEALPIPKMPTGS1
SCHEMBL4623911 0.77 AKR1C3 (0.42) CYP1A2CAPN1KMT2A
SCHEMBL4450793 0.68 SLC6A2 (0.44) CYP1A2EPHX1TAAR1
SCHEMBL7197326 0.67 CAPN1 (0.44) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL12556390 0.66 HSD17B10 (0.45) PTGS1FOLH1MEN1KMT2A
SCHEMBL3961925 0.65 CYP1A2 (0.55) CYP1A2MMEALPIPKMPTGS1
Phenylacetic Acid SCHEMBL28089878 0.65 AKR1B1 (0.68) PTGS1MEN1KMT2A
SCHEMBL2928010 0.65 CYP1A2 (0.55) CYP1A2MMEALPIPKMPTGS1
SCHEMBL9287878 0.65 POLB (0.44) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL6132238 0.65 ACE2 (0.36) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2404962-B1 Softener preparations with good gelling characteristics LANXESS DEUTSCHLAND GMBH (DE) 2013-01-16 EP disclosed
EP-2404962-A1 Softener preparations with good gelling characteristics LANXESS Deutschland GmbH (DE) 2012-01-11 EP disclosed