Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4673594 | 0.87 | PPARG (0.40) | PPARGPPARABCHEACHE | |
| SCHEMBL1720631 | 0.79 | PPARG (0.63) | PPARGPPARA | |
| SCHEMBL1720625 | 0.79 | PPARG (0.63) | PPARGPPARA | |
| SCHEMBL29930767 | 0.75 | FFAR1 (0.59) | PPARGPPARAPPARD | |
| SCHEMBL1720162 | 0.75 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL1720166 | 0.75 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL29930486 | 0.74 | MCL1 (0.43) | — | |
| SCHEMBL1719751 | 0.73 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL1719745 | 0.73 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL29930415 | 0.73 | MCL1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569904-A4 | SUBSTITUTED ARYLALCANOIC ACID DERIVATIVES AS PPAR PAN AGONISTS WITH POTENT ANTIHYPERGLYCEMIC AND ANTIHYPERLIPIDEMIC ACTIVITY | SHENZHEN CHIPSCREEN BIOSCIENCE (CN) | 2008-04-16 | — | — | EP | disclosed |
| EP-1569904-A1 | SUBSTITUTED ARYLALCANOIC ACID DERIVATIVES AS PPAR PAN AGONISTS WITH POTENT ANTIHYPERGLYCEMIC AND ANTIHYPERLIPIDEMIC ACTIVITY | Shenzhen Chipscreen Biosciences Ltd. (CN) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004048333-A1 | SUBSTITUTED ARYLALCANOIC ACID DERIVATIVES AS PPAR PAN AGONISTS WITH POTENT ANTIHYPERGLYCEMIC AND ANTIHYPERLIPIDEMIC ACTIVITY | SHENZHEN CHIPSCREEN BIOSCIENCES LTD. (US) | 2004-06-10 | — | — | WO | disclosed |