SCHEMBL467388

SCHEMBL467388

C1=C(C2=N/NCCCCC/2)\CCCCCC/1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.34
JAK2 O60674 1/20 0.33
JAK1 P23458 1/20 0.33
JAK3 P52333 1/20 0.33
TYMP P19971 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
CCNE1 P24864 1/20 0.31
CDK2 P24941 1/20 0.31
PSMB5 P28074 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL467389 1.00 ELANE (0.34) ELANEJAK2JAK1JAK3TYMP
SCHEMBL1086664 1.00 ELANE (0.34) ELANEJAK2JAK1JAK3TYMP
SCHEMBL37842 1.00 ELANE (0.34) ELANEJAK2JAK1JAK3TYMP
SCHEMBL5077 1.00 ELANE (0.34) ELANEJAK2JAK1JAK3TYMP
SCHEMBL37841 1.00 ELANE (0.34) ELANEJAK2JAK1JAK3TYMP
SCHEMBL5078 1.00 ELANE (0.34) ELANEJAK2JAK1JAK3TYMP
SCHEMBL1086667 1.00 ELANE (0.34) ELANEJAK2JAK1JAK3TYMP
SCHEMBL10564949 1.00 ELANE (0.34) ELANEJAK2JAK1JAK3TYMP
SCHEMBL8824597 1.00 ELANE (0.34) ELANEJAK2JAK1JAK3TYMP
SCHEMBL31298555 1.00 ELANE (0.34) ELANEJAK2JAK1JAK3TYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118772145-A Diazabicyclooctene Process for the preparation of compounds 上海医药工业研究院有限公司 2024-10-15 CN claimed
US-6013777-A REACTING CHROMOGEN IN APROTIC SOLVENT IN PRESENCE OF BASIC CATALYST TO FORM CARBAMATE-CONTAINING SOLUBLE DYES EXHIBITING SOLID STATE FLUORESCENCE IN THE UV RANGE CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-01-11 US claimed
CN-118772145-B Diazabicyclooctene Process for the preparation of compounds 上海医药工业研究院有限公司 2025-10-10 CN disclosed
CN-118772145-A Diazabicyclooctene Process for the preparation of compounds 上海医药工业研究院有限公司 2024-10-15 CN disclosed
CN-118772145-A Diazabicyclooctene Process for the preparation of compounds 上海医药工业研究院有限公司 2024-10-15 CN disclosed
EP-2909249-B1 CORE SHELL RUBBER MODIFIED SOLID EPOXY RESINS DOW GLOBAL TECHNOLOGIES LLC (US) 2019-07-31 EP disclosed
EP-3134448-B1 POLYURETHANE-ACRYLATE EPOXY ADHESIVE DOW GLOBAL TECHNOLOGIES LLC (US) 2018-09-26 EP disclosed
US-10066136-B2 Polyurethane-acrylate epoxy adhesive DOW GLOBAL TECHNOLOGIES LLC (US) 2018-09-04 US disclosed
US-9701851-B2 Core shell rubber modified solid epoxy resins DOW GLOBAL TECHNOLOGIES LLC (US) 2017-07-11 US disclosed
EP-2385970-B1 METAL STABILIZERS FOR EPOXY RESINS BLUE CUBE IP LLC (US) 2017-03-01 EP disclosed
EP-3134448-A1 POLYURETHANE-ACRYLATE EPOXY ADHESIVE Dow Global Technologies LLC (US) 2017-03-01 EP disclosed
EP-0648770-A2 Pyrrolo(3,4-c)pyrroles CIBA-GEIGY AG (CH) 1995-04-19 EP disclosed
EP-0648817-A1 Novel fluorescent dyes CIBA-GEIGY AG (CH) 1995-04-19 EP disclosed
EP-0499924-B1 Process for the preparation of dialkyle carbonates BAYER AG (DE) 1994-10-05 EP disclosed
US-5218135-A Catalytic carboxylation of alkylene oxide, then transesterification with alcohol BAYER AKTIENGESELLSCHAFT (DE) 1993-06-08 US disclosed
EP-0499924-A1 Process for the preparation of dialkyle carbonates BAYER AG (DE) 1992-08-26 EP disclosed
EP-0275728-B1 STEROIDS CONTAINING A KETO GROUP AT POSITION 23, THEIR PREPARATION, THEIR USE IN THE PREPARATION OF COMPOUNDS OF THE 20-KETOPREGNANE SERIES, AND INTERMEDIATES OF THIS USE ROUSSEL-UCLAF (FR) 1991-05-29 EP disclosed
US-4950428-A TWENTY KETO PREGNANES; PHARMACOLOGICAL PROPERTIES; STARTING MATERIALS FOR RECONSTRUCTION OF DEOXYCORTISONE CHAIN ROUSSEL UCLAF (FR) 1990-08-21 US disclosed
US-4847014-A CHEMICAL INTERMEDIATES, DEHYDROHALOGENATION ROUSSEL UCLAF (FR) 1989-07-11 US disclosed
EP-0275728-A1 Steroids containing a keto group at position 23, their preparation, their use in the preparation of compounds of the 20-ketopregnane series, and intermediates of this use ROUSSEL-UCLAF (FR) 1988-07-27 EP disclosed