Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679303 | 0.81 | — | — | |
| SCHEMBL5780870 | 0.81 | — | — | |
| SCHEMBL19924496 | 0.81 | CCR1 (0.47) | PDE10ACYP1A2 | |
| SCHEMBL5441582 | 0.80 | MCHR1 (0.32) | — | |
| SCHEMBL1500426 | 0.78 | — | — | |
| SCHEMBL295035 | 0.75 | CYP1A2 (0.54) | CYP1A2 | |
| SCHEMBL6233725 | 0.75 | PDE10A (0.31) | PDE10A | |
| SCHEMBL5801074 | 0.74 | CYP1A2 (0.39) | CYP1A2 | |
| SCHEMBL27243819 | 0.73 | SRC (0.34) | — | |
| SCHEMBL153778 | 0.71 | CYSLTR1 (0.53) | PDE10ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416933-B8 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEN INC (US) | 2008-08-27 | — | — | EP | disclosed |
| EP-1416933-A1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | Amgem, Inc. (US) | 2004-05-12 | — | — | EP | disclosed |
| EP-1309585-A2 | NOVEL INDOLE DERIVATIVES AND THEIR USE AS MEDICAMENTS | Zentaris AG (DE) | 2003-05-14 | — | — | EP | disclosed |
| WO-2003009847-A1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEM, INC. (US) | 2003-02-06 | — | — | WO | disclosed |
| WO-2002010152-A2 | NOVEL INDOLE DERIVATIVES AND THEIR USE AS MEDICAMENTS | ZENTARIS AG (DE) | 2002-02-07 | — | — | WO | disclosed |