Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 0.48 |
| ▸ | MC3R | P41968 | 4/20 | 0.48 |
| ▸ | MC5R | P33032 | 3/20 | 0.48 |
| ▸ | MC1R | Q01726 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5475767 | 0.88 | MC4R (0.58) | MC4RMC3RMC5RMC1R | |
| SCHEMBL4682255 | 0.78 | AKT1 (0.62) | MC4R | |
| SCHEMBL4523143 | 0.73 | MC4R (0.63) | MC4RMC3RMC5RMC1R | |
| SCHEMBL14537172 | 0.71 | MC4R (0.53) | MC4RMC3RMC5RMC1R | |
| SCHEMBL4681208 | 0.70 | MC4R (0.81) | MC4R | |
| SCHEMBL14640075 | 0.69 | MC4R (0.76) | MC4RMC3RMC5RMC1R | |
| SCHEMBL4506598 | 0.68 | MC4R (0.61) | MC4RMC3RMC5RMC1R | |
| SCHEMBL4680491 | 0.68 | MC4R (0.55) | MC4RMC3RMC5RMC1R | |
| SCHEMBL14356082 | 0.68 | MC4R (0.51) | MC4RMC3RMC5R | |
| SCHEMBL14356076 | 0.68 | MC4R (0.51) | MC4RMC3RMC5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417190-B1 | SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEN INC (US) | 2008-10-22 | — | — | EP | claimed |