SCHEMBL4676401

SCHEMBL4676401

CC([O])C(=O)OC1CCCC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.49
EPHX1 P07099 2/20 0.42
NAAA Q02083 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.38
HTT P42858 1/20 0.38
CA12 O43570 2/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
CYP2C19 P33261 1/20 0.36
GAA P10253 1/20 0.35
MMP2 P08253 2/20 0.35
MMP9 P14780 2/20 0.35
ANPEP P15144 2/20 0.35
LTA4H P09960 1/20 0.35
LAP3 P28838 1/20 0.35
NPEPPS P55786 1/20 0.35
ERAP2 Q6P179 1/20 0.35
ERAP1 Q9NZ08 1/20 0.35
CYP2D6 P10635 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4675856 0.98 CYP19A1 (0.51) CYP19A1EPHX1NAAAL3MBTL1HTT
SCHEMBL4676656 0.95 CYP19A1 (0.45) CYP19A1EPHX1NAAAL3MBTL1HTT
SCHEMBL4677738 0.91
SCHEMBL2419961 0.84 CYP19A1 (0.50) CYP19A1EPHX1NAAAL3MBTL1HTT
SCHEMBL1928011 0.83 CYP19A1 (0.50) CYP19A1EPHX1NAAAL3MBTL1HTT
SCHEMBL2250233 0.82 CYP19A1 (0.49) CYP19A1EPHX1NAAAL3MBTL1HTT
SCHEMBL8984845 0.82 CYP19A1 (0.53) CYP19A1EPHX1NAAAL3MBTL1HTT
SCHEMBL753308 0.82 CYP19A1 (0.53) CYP19A1EPHX1NAAAL3MBTL1HTT
SCHEMBL25404680 0.80 CYP19A1 (0.47) CYP19A1EPHX1NAAAL3MBTL1HTT
SCHEMBL13543466 0.80 CYP19A1 (0.47) CYP19A1EPHX1NAAAL3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1095935-B1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL CO (JP) 2008-12-17 EP disclosed
EP-1101761-B1 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL CO (JP) 2005-08-17 EP disclosed
US-6410484-B1 ACTIVE MATERIAL; CONTROLLING WEEDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-25 US disclosed
US-6339155-B1 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-15 US disclosed
EP-1101761-A2 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-23 EP disclosed
EP-1095935-A1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-02 EP disclosed