SCHEMBL467695

SCHEMBL467695

OC[C@H]1OC(ON=CCc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.56
SLC28A3 Q9HAS3 3/20 0.48
PPARG P37231 1/20 0.48
PPARD Q03181 1/20 0.48
PPARA Q07869 1/20 0.48
KDM4E B2RXH2 2/20 0.48
MAPT P10636 2/20 0.48
POLB P06746 1/20 0.48
GAA P10253 1/20 0.48
G6PD P11413 1/20 0.48
MAPK1 P28482 1/20 0.48
ADRA1A P35348 1/20 0.48
PTGS2 P35354 1/20 0.48
SLC5A1 P13866 6/20 0.47
SLC5A2 P31639 4/20 0.47
HPGD P15428 2/20 0.45
HSD17B10 Q99714 2/20 0.45
CYP3A4 P08684 1/20 0.45
THRB P10828 1/20 0.45
CYP2C9 P11712 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28867299 0.76 TYR (0.66) TYRSLC28A3PPARGPPARDPPARA
Salidroside SCHEMBL13576885 0.73 MAOB (0.62) TYRSLC28A3PPARGPPARDPPARA
Salidroside SCHEMBL13577088 0.73 MAOB (0.62) TYRSLC28A3PPARGPPARDPPARA
Salidroside SCHEMBL1438615 0.73 MAOB (0.62) TYRSLC28A3PPARGPPARDPPARA
Salidroside SCHEMBL148079 0.73 MAOB (0.62) TYRSLC28A3PPARGPPARDPPARA
Salidroside SCHEMBL17594810 0.73 MAOB (0.62) TYRSLC28A3PPARGPPARDPPARA
Salidroside SCHEMBL15015045 0.73 MAOB (0.62) TYRSLC28A3PPARGPPARDPPARA
Salidroside SCHEMBL17580247 0.73 MAOB (0.62) TYRSLC28A3PPARGPPARDPPARA
Salidroside SCHEMBL17922525 0.73 MAOB (0.62) TYRSLC28A3PPARGPPARDPPARA
Salidroside SCHEMBL28707078 0.73 MAOB (0.62) TYRSLC28A3PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150232889-A1 Method of Producing a Low Molecular Weight Organic Compound in a Cell EVOLVA SA (CH) 2015-08-20 US disclosed
US-8986950-B2 Method of producing a low molecular weight organic compound in a cell EVOLVA SA (CH) 2015-03-24 US disclosed
EP-1649029-B1 A METHOD OF PRODUCING A LOW MOLECULAR WEIGHT PLANT SECONDARY METABOLITE IN A YEAST CELL EVOLVA SA (CH) 2014-12-17 EP disclosed
US-8105786-B2 Method of producing a low molecular weight organic compound in a cell EVOLVA SA (CH) 2012-01-31 US disclosed
US-20110318793-A1 Method of Producing a Low Molecular Weight Organic Compound in a Cell EVOLVA SA (CH) 2011-12-29 US disclosed
EP-2388333-A2 A method of producing a low molecular weight organic compound in a cell Evolva SA (CH) 2011-11-23 EP disclosed
US-8041750-B2 Method and apparatus for organizing and playing data YAHOO! INC. (US) 2011-10-18 US disclosed
US-20110136177-A1 Method of Producing a Low Molecular Weight Organic Compound in a Cell BLMaps (DK) 2011-06-09 US disclosed
US-7846697-B2 Method of producing a low molecular weight organic compound in a cell BLMaps (DK) 2010-12-07 US disclosed
US-20060275877-A1 Method of producing a low molecular weight organic compound in a cell DANSTAR FERMENT AG (CH) 2006-12-07 US disclosed
EP-1649029-A1 A METHOD OF PRODUCING A LOW MOLECULAR WEIGHT ORGANIC COMPOUND IN A CELL Poalis A/S (DK) 2006-04-26 EP disclosed
EP-1510586-A1 A method of producing a low molecular weight organic compound in a cell Poalis A/S (DK) 2005-03-02 EP disclosed
WO-2004111254-A1 A METHOD OF PRODUCING A LOW MOLECULAR WEIGHT ORGANIC COMPOUND IN A CELL POALIS A/S (DK) 2004-12-23 WO disclosed