Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641458 | 1.00 | MEN1 (0.46) | MEN1KMT2AGRIN1GRIN2BALDH1A1 | |
| SCHEMBL4640534 | 0.89 | TRPV1 (0.47) | — | |
| SCHEMBL5435650 | 0.88 | GRIN1 (0.52) | MEN1KMT2AGRIN1GRIN2B | |
| SCHEMBL4640637 | 0.88 | GRIN1 (0.52) | MEN1KMT2AGRIN1GRIN2B | |
| SCHEMBL3833294 | 0.88 | MEN1 (0.43) | MEN1KMT2AGRIN1GRIN2B | |
| SCHEMBL3833265 | 0.88 | MEN1 (0.43) | MEN1KMT2AGRIN1GRIN2B | |
| SCHEMBL4640570 | 0.87 | MEN1 (0.45) | MEN1KMT2AALDH1A1 | |
| SCHEMBL14099215 | 0.85 | MEN1 (0.50) | MEN1KMT2AALDH1A1 | |
| SCHEMBL4640597 | 0.83 | — | — | |
| SCHEMBL5273882 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824837-B1 | SUBSTITUTED N-SULFONYLAMINOBENZYL-2-PHENOXY ACETAMIDE COMPOUNDS | PFIZER (US) | 2008-08-13 | — | — | EP | disclosed |