Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4678923 | 0.94 | MC4R (0.73) | MC4R | |
| SCHEMBL4681198 | 0.93 | MC4R (0.68) | MC4R | |
| SCHEMBL4681208 | 0.90 | MC4R (0.81) | MC4R | |
| SCHEMBL4510874 | 0.87 | MC4R (0.75) | MC4R | |
| SCHEMBL4524337 | 0.84 | MC4R (0.77) | MC4R | |
| SCHEMBL4682103 | 0.84 | MC4R (0.77) | MC4R | |
| SCHEMBL4529570 | 0.83 | MC4R (0.85) | MC4R | |
| SCHEMBL4524336 | 0.82 | MC4R (0.88) | MC4R | |
| SCHEMBL4682100 | 0.82 | MC4R (0.88) | MC4R | |
| SCHEMBL5482734 | 0.82 | MC4R (0.75) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417190-B1 | SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEN INC (US) | 2008-10-22 | — | — | EP | claimed |