Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 2/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4685732 | 0.92 | KMT2A (0.44) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL4678229 | 0.91 | ACKR3 (0.43) | UBE2MDCUN1D1EPHX2LMNA | |
| SCHEMBL4682972 | 0.91 | PPARA (0.40) | KMT2AMEN1SMN1; SMN2CYP2C19LMNA | |
| SCHEMBL4679962 | 0.90 | ACKR3 (0.45) | KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL4679955 | 0.90 | ACKR3 (0.45) | KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL4678644 | 0.90 | CYP2C19 (0.41) | KMT2AMEN1MAPTSMN1; SMN2CYP2C19 | |
| Hydrochloric Acid SCHEMBL4682704 | 0.89 | NR1H4 (0.42) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL4679674 | 0.89 | ACKR3 (0.46) | SMN1; SMN2 | |
| SCHEMBL4680425 | 0.89 | NPC1 (0.40) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL4683523 | 0.89 | ACKR3 (0.41) | KMT2AMEN1SMN1; SMN2LMNAPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1058680-B1 | 2-ARYLETHYL-(PIPERIDIN-4-YLMETHYL)AMINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2008-07-09 | — | — | EP | disclosed |
| US-6319920-B1 | MUSCARINIC RECEPTOR ANTAGONIST USED IN GASTROINTESTINAL, GENITOURINARY TRACT, RESPIRATORY TRACT, CARDIOVASCULAR SYSTEM, CENTRAL NERVOUS SYSTEM DISORDERS AND IN ANESTHESIOLOGY AND OPHTHALMOLOGY | SYNTEX (U.S.A.) LLC | 2001-11-20 | — | — | US | disclosed |