Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 7/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 3/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4685232 | 0.94 | NR1H4 (0.43) | NR1H4ACKR3PPARAPPARGKCNK9 | |
| Trifluoroacetic Acid SCHEMBL4682096 | 0.94 | NR1H4 (0.43) | TSHRNR1H4ACKR3PPARAPPARG | |
| Trifluoroacetic Acid SCHEMBL4678472 | 0.93 | NR1H4 (0.44) | NR1H4ACKR3PPARAPPARGKCNK9 | |
| Trifluoroacetic Acid SCHEMBL4685661 | 0.92 | NR1H4 (0.43) | NR1H4ACKR3PPARAPPARGKCNK9 | |
| Trifluoroacetic Acid SCHEMBL4682457 | 0.92 | NR1H4 (0.43) | NR1H4ACKR3PPARAPPARGKCNK9 | |
| Trifluoroacetic Acid SCHEMBL4683129 | 0.91 | NR1H4 (0.43) | NR1H4ACKR3PPARAPPARGKCNK9 | |
| Trifluoroacetic Acid SCHEMBL4682510 | 0.91 | NR1H4 (0.43) | NR1H4ACKR3PPARAPPARGKCNK9 | |
| Trifluoroacetic Acid SCHEMBL4678584 | 0.91 | ACKR3 (0.44) | NR1H4ACKR3PPARAPPARGKCNK9 | |
| Trifluoroacetic Acid SCHEMBL4683184 | 0.91 | NR1H4 (0.42) | NR1H4ACKR3PPARAPPARGKCNK9 | |
| Trifluoroacetic Acid SCHEMBL4679858 | 0.91 | NR1H4 (0.42) | NR1H4ACKR3PPARAPPARGKCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1058680-B1 | 2-ARYLETHYL-(PIPERIDIN-4-YLMETHYL)AMINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2008-07-09 | — | — | EP | disclosed |
| US-6319920-B1 | MUSCARINIC RECEPTOR ANTAGONIST USED IN GASTROINTESTINAL, GENITOURINARY TRACT, RESPIRATORY TRACT, CARDIOVASCULAR SYSTEM, CENTRAL NERVOUS SYSTEM DISORDERS AND IN ANESTHESIOLOGY AND OPHTHALMOLOGY | SYNTEX (U.S.A.) LLC | 2001-11-20 | — | — | US | disclosed |