⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9903249 | 0.53 | — | — | |
| SCHEMBL1034170 | 0.45 | — | — | |
| SCHEMBL1052909 | 0.41 | — | — | |
| SCHEMBL1714180 | 0.38 | — | — | |
| SCHEMBL8466155 | 0.38 | — | — | |
| SCHEMBL29105 | 0.38 | — | — | |
| Dibromodifluoromethane SCHEMBL102197 | 0.38 | — | — | |
| SCHEMBL11807704 | 0.38 | — | — | |
| SCHEMBL1037620 | 0.38 | — | — | |
| Teflurane SCHEMBL566553 | 0.36 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333834-B1 | ANTIINFLAMMATION AGENTS | AMGEN INC (US) | 2008-04-23 | — | — | EP | claimed |
| US-20070135464-A1 | Antiinflammation agents | AMGEN, INC. | 2007-06-14 | — | — | US | claimed |
| US-7186841-B2 | (2-imidazolyl)quinolin-4-yl aldehydes; immunomodulators, antiproliferative agents; metabolic disorders | AMGEN INC. (US) | 2007-03-06 | — | — | US | claimed |
| US-7176314-B2 | IkB kinases (IKK) enzyme inhibitors, a imidazole-5-yl-quinoline derivatives compounds | AMGEN, INC. (US) | 2007-02-13 | — | — | US | claimed |
| EP-1333834-A4 | ANTIINFLAMMATION AGENTS | AMGEN INC (US) | 2007-01-17 | — | — | EP | claimed |
| US-20050043330-A1 | Antiinflammation agents | AMGEN INC. (US) | 2005-02-24 | — | — | US | claimed |
| US-6846828-B2 | Aminopyrimidine and aminopyridine anti-inflammation agents | ROCHE PALO ALTO LLC (US) | 2005-01-25 | — | — | US | claimed |
| US-6846834-B2 | Compounds contain fused carbocyclic or heterocyclic rings; modulate expression and/or function of proteins involved in inflammation, metabolism and cell proliferation | AMGEN INC. (US) | 2005-01-25 | — | — | US | claimed |
| EP-1444223-A1 | AMINOPYRIMIDINES AND -PYRIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-08-11 | — | — | EP | claimed |
| US-20030181472-A1 | Inflammation modulators | TULARIK INC. | 2003-09-25 | — | — | US | claimed |
| EP-1333834-A2 | ANTIINFLAMMATION AGENTS | Tularik Inc. (US) | 2003-08-13 | — | — | EP | claimed |
| US-20030144303-A1 | Aminopyrimidine and aminopyridine anti-inflammation agents | SYNTEX (U.S.A.) LLC | 2003-07-31 | — | — | US | claimed |
| WO-2003048152-A2 | INFLAMMATION MODULATORS | TULARIK INC. (US) | 2003-06-12 | — | — | WO | claimed |
| WO-2003040131-A1 | AMINOPYRIMIDINES AND PYRIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-15 | — | — | WO | claimed |
| US-20020161004-A1 | Antiinflammation agents | SYNTEX (U.S.A.) LLC (US) | 2002-10-31 | — | — | US | claimed |
| WO-2002041843-A2 | ANTIINFLAMMATION AGENTS | TULARIK INC. (US) | 2002-05-30 | — | — | WO | claimed |
| EP-1333834-B1 | ANTIINFLAMMATION AGENTS | AMGEN INC (US) | 2008-04-23 | — | — | EP | disclosed |
| US-20070135464-A1 | Antiinflammation agents | AMGEN, INC. | 2007-06-14 | — | — | US | disclosed |
| WO-2002041843-A2 | ANTIINFLAMMATION AGENTS | TULARIK INC. (US) | 2002-05-30 | — | — | WO | disclosed |
| WO-2002020512-A1 | IMIDAZOLO-5-YL-2-ANILINO-PYRIMIDINES AS AGENTS FOR THE INHIBITION OF THE CELL PROLIFERATION | ASTRAZENECA AB (SE) | 2002-03-14 | — | — | WO | disclosed |