SCHEMBL4680225

SCHEMBL4680225

[CH2]C(=C)COC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1058224 0.74
SCHEMBL1706297 0.71
SCHEMBL87087 0.71
SCHEMBL12766610 0.69
SCHEMBL19417110 0.69
Methane SCHEMBL27339622 0.69
SCHEMBL8804302 0.69
SCHEMBL17239086 0.69
SCHEMBL220766 0.69
SCHEMBL87261 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0945448-B1 5-ALKOXY-2(3H)-OXAZOLONE COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF UBE INDUSTRIES (JP) 2008-11-26 EP disclosed
CN-1174971-C Morpholino ethers 葛兰素惠尔康有限公司 2004-11-10 CN disclosed
US-6645960-B1 Antiprotozoa agents for animal or human infections GLAXO WELLCOME S.A. (ES) 2003-11-11 US disclosed
US-6436930-B1 FOR TREATMENT OF INFECTIONS BY CANDIDA ALBICANS BRISTOL-MYERS SQUIBB COMPANY 2002-08-20 US disclosed
EP-1228049-A1 ANTIFUNGAL SORDARICIN DERIVATIVES Glaxo Wellcome S.A. (ES) 2002-08-07 EP disclosed
US-6414160-B1 REACTING 5-ALKOXY-2(3H)OXAZOLONE COMPOUND WITH ALDEHYDE COMPOUND IN PRESENCE OF LEWIS ACID CATALYST UBE INDUSTRIES, LTD. (JP) 2002-07-02 US disclosed
US-6410528-B1 FUNGICIDES, ANTIPROTOZOA AGENT GLAXO WELLCOME S.A. (ES) 2002-06-25 US disclosed
US-20020035073-A1 Novel thio derivatives of sordarin as antifungal agents BRISTOL-MYERS SQUIBB COMPANY 2002-03-21 US disclosed
WO-2002022567-A1 NOVEL THIO DERIVATIVES OF SORDARIN AS ANTIFUNGAL AGENTS BRISTOL-MYERS SQUIBB COMPANY (US) 2002-03-21 WO disclosed
CN-1309651-A Morpholine ethers GLAXO WELLCOME SA (ES) 2001-08-22 CN disclosed
WO-2001034583-A1 ANTIFUNGAL SORDARICIN DERIVATIVES GLAXO WELLCOME SA (ES) 2001-05-17 WO disclosed
EP-1077959-A1 MORPHOLINO ETHERS Glaxo Wellcome S.A. (ES) 2001-02-28 EP disclosed
EP-1000937-A1 PROCESS FOR PRODUCING 4-ALKOXYCARBONYL-2-OXAZOLIDINONE COMPOUNDS UBE INDUSTRIES LIMITED (JP) 2000-05-17 EP disclosed
US-6020496-A 5-alkoxy-2(3H)-oxazolone compounds and process for preparing the same UBE INDUSTRIES, LTD. (JP) 2000-02-01 US disclosed
WO-1999058512-A1 MORPHOLINO ETHERS GLAXO WELLCOME S.A. (ES) 1999-11-18 WO disclosed
EP-0945448-A1 5-ALKOXY-2(3H)-OXAZOLONE COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF UBE INDUSTRIES, LTD. (JP) 1999-09-29 EP disclosed