Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4681451 | 0.94 | PTGER1 (1.00) | PTGER1CYP1A2 | |
| SCHEMBL4096041 | 0.92 | PTGER1 (1.00) | PTGER1CYP1A2 | |
| SCHEMBL4683864 | 0.90 | PTGER1 (1.00) | PTGER1CYP1A2 | |
| SCHEMBL4680673 | 0.87 | PTGER1 (1.00) | PTGER1CYP1A2 | |
| SCHEMBL4684584 | 0.87 | PTGER1 (0.76) | PTGER1CYP1A2 | |
| SCHEMBL4684647 | 0.86 | PTGER1 (0.85) | PTGER1CYP1A2 | |
| SCHEMBL4680603 | 0.85 | PTGER1 (1.00) | PTGER1CYP1A2 | |
| SCHEMBL4686673 | 0.85 | PTGER1 (1.00) | PTGER1CYP1A2 | |
| SCHEMBL4686760 | 0.84 | PTGER1 (1.00) | PTGER1CYP1A2 | |
| SCHEMBL4095810 | 0.84 | PTGER1 (0.85) | PTGER1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675832-B1 | HETEROCYCLYL COMPOUNDS | GLAXO GROUP LTD (GB) | 2008-02-20 | — | — | EP | claimed |
| EP-1675832-B1 | HETEROCYCLYL COMPOUNDS | GLAXO GROUP LTD (GB) | 2008-02-20 | — | — | EP | disclosed |
| US-20070060596-A1 | Heterocyclyl compounds | GLAXO GROUP LIMITED (GB) | 2007-03-15 | — | — | US | disclosed |
| US-20070060596-A1 | Heterocyclyl compounds | GLAXO GROUP LIMITED (GB) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060596-A1 | Heterocyclyl compounds | F9, F12, CYP2C9 | PTGER1 1257/4885CYP1A2 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.