Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 20/20 | 0.75 |
| ▸ | CCR3 | P51677 | 20/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4684383 | 0.91 | HRH1 (0.75) | HRH1CCR3KCNH2 | |
| SCHEMBL4035142 | 0.86 | HRH1 (0.73) | HRH1CCR3KCNH2 | |
| SCHEMBL4040955 | 0.86 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL4680515 | 0.85 | HRH1 (0.69) | HRH1CCR3KCNH2 | |
| SCHEMBL4681914 | 0.85 | HRH1 (0.75) | HRH1CCR3KCNH2 | |
| SCHEMBL4682712 | 0.85 | HRH1 (0.83) | HRH1CCR3KCNH2 | |
| SCHEMBL4682696 | 0.83 | HRH1 (0.77) | HRH1CCR3KCNH2 | |
| SCHEMBL4677977 | 0.83 | HRH1 (0.82) | HRH1CCR3KCNH2 | |
| SCHEMBL4681708 | 0.83 | HRH1 (0.79) | HRH1CCR3KCNH2 | |
| SCHEMBL4684317 | 0.83 | HRH1 (0.82) | HRH1CCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487817-B1 | PIPERIDINE DERIVATIVES USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2008-06-04 | — | — | EP | disclosed |