Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | KDM4A | O75164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4677528 | 0.92 | KMT2A (0.58) | CYP2C9CYP2C19CYP2D6KMT2AEPHX2 | |
| SCHEMBL4677539 | 0.92 | KMT2A (0.58) | CYP2C9CYP2C19CYP2D6KMT2AEPHX2 | |
| SCHEMBL10627851 | 0.87 | KMT2A (0.77) | CYP2C9CYP2C19CYP2D6KMT2AEPHX2 | |
| SCHEMBL10423181 | 0.87 | KMT2A (0.77) | CYP2C9CYP2C19CYP2D6KMT2AEPHX2 | |
| SCHEMBL10611159 | 0.87 | KMT2A (0.77) | CYP2C9CYP2C19CYP2D6KMT2AEPHX2 | |
| Hydrochloric Acid SCHEMBL10632778 | 0.85 | KMT2A (0.74) | CYP2C9CYP2C19CYP2D6KMT2AEPHX2 | |
| SCHEMBL4676692 | 0.82 | SMN1; SMN2 (0.53) | KMT2AKDM4EEPHX1ALDH1A1 | |
| SCHEMBL4676219 | 0.82 | SMN1; SMN2 (0.53) | KMT2AKDM4EEPHX1ALDH1A1 | |
| SCHEMBL4675943 | 0.80 | KDM4E (0.55) | CYP2C19CYP2D6KMT2AKDM4ECYP1A2 | |
| SCHEMBL4676756 | 0.80 | KDM4E (0.55) | CYP2C19CYP2D6KMT2AKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633702-B1 | PROTEASE INHIBITORS | PROZYMEX AS (DK) | 2008-07-02 | — | — | EP | claimed |