SCHEMBL4681925

SCHEMBL4681925

CCC(CC)C(=O)Nc1ccccc1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.86
KMT2A Q03164 4/20 0.86
SMN1; SMN2 Q16637 3/20 0.75
ALDH1A1 P00352 2/20 0.67
MAPT P10636 1/20 0.67
MAPK1 P28482 1/20 0.67
TSHR P16473 1/20 0.61
CA1 P00915 1/20 0.60
CA2 P00918 1/20 0.60
CA7 P43166 1/20 0.60
CA14 Q9ULX7 1/20 0.60
HTT P42858 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
RAB9A P51151 1/20 0.58
LMNA P02545 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
GAA P10253 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9861467 0.90 KMT2A (0.71) MEN1KMT2ASMN1; SMN2ALDH1A1MAPT
SCHEMBL16106143 0.89 MEN1 (0.73) MEN1KMT2ASMN1; SMN2ALDH1A1MAPT
SCHEMBL12335729 0.89 MEN1 (0.71) MEN1KMT2ASMN1; SMN2ALDH1A1MAPT
SCHEMBL13150830 0.88 MEN1 (0.69) MEN1KMT2ASMN1; SMN2ALDH1A1MAPT
SCHEMBL3923314 0.86 MEN1 (0.89) MEN1KMT2ASMN1; SMN2ALDH1A1MAPT
SCHEMBL29269293 0.86 MEN1 (0.67) MEN1KMT2ASMN1; SMN2ALDH1A1MAPT
SCHEMBL11652739 0.85 MEN1 (0.86) MEN1KMT2ASMN1; SMN2ALDH1A1MAPT
SCHEMBL11518363 0.85 MEN1 (0.81) MEN1KMT2ASMN1; SMN2ALDH1A1MAPT
SCHEMBL20621920 0.85 MEN1 (0.65) MEN1KMT2ASMN1; SMN2ALDH1A1MAPT
SCHEMBL14853295 0.84 MEN1 (0.64) MEN1KMT2ASMN1; SMN2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110612119-A Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents 西雅图儿童医院(DBA西雅图儿童研究所) 2019-12-24 CN claimed
WO-2018148224-A1 PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) 2018-08-16 WO claimed
CN-1528764-A Herbicide O, O-dimethyl-1- (2, 4-dichlorophenoxy acetoxyl) ethyl phosphonate and its weeding composition 华中师范大学 2004-09-15 CN claimed
CN-1099372-A Medicated fertilizer for dressing, pests-controlling and chemical weeding and using method thereof ZENG ZHIZHONG (CN) 1995-03-01 CN claimed
EP-0565593-A1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO COMPANY (US) 1993-10-20 EP claimed
CN-1055357-A N-alkynes-2-chlorine-acetyl-phenyl derivative and the weedicide that contains this compound CENTRAL GLASS CO LTD (JP) 1991-10-16 CN claimed
EP-0194985-A2 Method for the regulation of the natural growth of turf grass Monsanto Company (US) 1986-09-17 EP claimed
US-4217131-A N-/BUTOXYMETHYL/-2-CHLORO-2',6'-DIETHYLACETANILIDE, A-/B-NAPHTHOXYL/PROPIONIC ACID DERIVATIVE MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1980-08-12 US claimed
EP-4291571-A2 ACTIVITY-INDUCIBLE FUSION PROTEINS HAVING A HEAT SHOCK PROTEIN 90 BINDING DOMAIN Seattle Children's Hospital d/b/a Seattle Children's Research Institute (US) 2023-12-20 EP disclosed
US-20230172981-A1 METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS SEATTLE CHILDRENS HOSPITAL DBA SEATTLE CHILDRENS RES INST (US) 2023-06-08 US disclosed
CN-115556441-A Decorative film and method for producing decorative molded body using same 日本聚丙烯株式会社 2023-01-03 CN disclosed
CN-115556446-A Decorative film and method for producing decorative molded body using same 日本聚丙烯株式会社 2023-01-03 CN disclosed
WO-2022174035-A2 ACTIVITY-INDUCIBLE FUSION PROTEINS HAVING A HEAT SHOCK PROTEIN 90 BINDING DOMAIN SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) 2022-08-18 WO disclosed
CN-113195594-B Silicone-polycarbonate copolymers, sealants including silicone-polycarbonate copolymers, and related methods 美国陶氏有机硅公司 2022-03-29 CN disclosed
CN-1048383-A Mycocide and preparation method thereof ICI PLC (GB) 1991-01-09 CN disclosed
CN-1042900-A Mycocide ICI PLC (GB) 1990-06-13 CN disclosed
EP-0368592-A1 Herbicidal compositions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-05-16 EP disclosed
CN-86103259-A The preparation method of novel pyrazole derivatives and application 1987-01-28 CN disclosed
EP-0194985-A2 Method for the regulation of the natural growth of turf grass Monsanto Company (US) 1986-09-17 EP disclosed
EP-0125059-A2 Herbicidal cyclohexane-1,3-dione derivatives ICI AUSTRALIA LIMITED (AU) 1984-11-14 EP disclosed