Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2287569 | 0.84 | MEN1 (0.64) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL10383501 | 0.82 | IDO1 (0.40) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL15527640 | 0.82 | MEN1 (0.62) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL13584733 | 0.80 | MEN1 (0.60) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL29518687 | 0.80 | MEN1 (0.60) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL10384384 | 0.80 | KMT2A (0.47) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL4678382 | 0.80 | MEN1 (0.49) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL8983449 | 0.80 | IDO1 (0.63) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL18201566 | 0.80 | MAPT (0.55) | KMT2AMEN1MAPTALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL13584417 | 0.79 | MEN1 (0.58) | KMT2AMEN1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392655-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2008-07-16 | — | — | EP | disclosed |
| EP-1198456-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2007-09-19 | — | — | EP | disclosed |
| US-4731396-A | Thermal stabilization of acetal polymers | CELANESE CORPORATION (US) | 1988-03-15 | — | — | US | disclosed |