Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 12/20 | 0.38 |
| ▸ | PPARA | Q07869 | 7/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4678018 | 0.80 | NPC1 (0.46) | NPC1ALDH1A1GAAPPARDPPARA | |
| SCHEMBL6221868 | 0.76 | NPC1 (0.52) | NPC1ALDH1A1GAAPPARDPPARA | |
| SCHEMBL5406405 | 0.76 | NPC1 (0.46) | NPC1ALDH1A1GAAPPARDPPARA | |
| SCHEMBL4854310 | 0.74 | NPC1 (0.50) | NPC1ALDH1A1GAAPPARDPPARA | |
| SCHEMBL4856478 | 0.74 | NPC1 (0.53) | NPC1ALDH1A1GAAPPARDPPARA | |
| SCHEMBL4856486 | 0.74 | NPC1 (0.53) | NPC1ALDH1A1GAAPPARDPPARA | |
| SCHEMBL4854315 | 0.74 | NPC1 (0.50) | NPC1ALDH1A1GAAPPARDPPARA | |
| SCHEMBL4882934 | 0.74 | NPC1 (0.50) | NPC1ALDH1A1GAAPPARDPPARA | |
| SCHEMBL3371882 | 0.74 | NPC1 (0.53) | NPC1ALDH1A1GAAPPARDPPARA | |
| SCHEMBL27650489 | 0.74 | NPC1 (0.56) | NPC1ALDH1A1GAAPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513796-B1 | PHENYLOXYALKANOIC ACID DERIVATIVES AS HPPAR ACTIVATORS | SMITHKLINE BEECHAM CORP (US) | 2008-02-13 | — | — | EP | disclosed |