Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4946005 | 0.86 | BACE1 (0.43) | BACE1BACE2 | |
| SCHEMBL2023415 | 0.86 | BACE1 (0.43) | BACE1BACE2 | |
| SCHEMBL2018791 | 0.83 | BACE1 (0.43) | BACE1BACE2 | |
| SCHEMBL2018789 | 0.83 | BACE1 (0.43) | BACE1BACE2 | |
| SCHEMBL2024027 | 0.83 | BACE1 (0.53) | BACE1BACE2 | |
| SCHEMBL2023745 | 0.83 | BACE1 (0.53) | BACE1BACE2 | |
| SCHEMBL12578958 | 0.80 | BACE1 (0.49) | BACE1BACE2 | |
| SCHEMBL5650748 | 0.78 | BACE1 (0.40) | BACE1BACE2 | |
| SCHEMBL4946010 | 0.78 | BACE1 (0.42) | BACE1BACE2 | |
| SCHEMBL5651224 | 0.77 | BACE1 (0.49) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740581-A4 | 2, 4, 6-SUBSTITUTED PYRIDYL DERIVATIVE COMPOUNDS USEFUL AS BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | MERCK & CO INC (US) | 2008-01-23 | — | — | EP | disclosed |
| EP-1740581-A1 | 2, 4, 6-SUBSTITUTED PYRIDYL DERIVATIVE COMPOUNDS USEFUL AS BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER\"S DISEASE | Merck and Co., Inc. (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005103043-A1 | 2, 4, 6-SUBSTITUTED PYRIDYL DERIVATIVE COMPOUNDS USEFUL AS BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER’S DISEASE | MERCK & CO., INC. (US) | 2005-11-03 | — | — | WO | disclosed |