Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13894764 | 0.82 | CYP19A1 (0.37) | EGLN3KMT2AMEN1FDPSCYP19A1 | |
| SCHEMBL10192307 | 0.82 | CYP19A1 (0.37) | EGLN3KMT2AMEN1FDPSCYP19A1 | |
| SCHEMBL7470887 | 0.79 | EGLN3 (0.37) | EGLN3KMT2AMEN1FDPSCYP19A1 | |
| SCHEMBL7470879 | 0.79 | EGLN3 (0.37) | EGLN3KMT2AMEN1FDPSCYP19A1 | |
| SCHEMBL171184 | 0.79 | — | — | |
| SCHEMBL7467012 | 0.79 | — | — | |
| SCHEMBL25022444 | 0.78 | TSHR (0.37) | EGLN3KMT2AMEN1CYP19A1 | |
| SCHEMBL22365186 | 0.77 | CYP19A1 (0.34) | EGLN3KMT2AMEN1FDPSCYP19A1 | |
| SCHEMBL12251302 | 0.75 | CYP19A1 (0.38) | EGLN3KMT2AMEN1FDPSCYP19A1 | |
| SCHEMBL1082326 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| CN-1039999-C | Vasopressin antagonist and oxytocin antagonist, process for their preparation and pharmaceutical compositions containing them | OTSUKA CHEMICAL CO LTD (JP) | 1998-09-30 | — | — | CN | disclosed |
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0620003-A1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |