Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4685531 | 0.89 | SMN1; SMN2 (0.48) | MEN1KMT2ATSHRGAANPSR1 | |
| Hydrochloric Acid SCHEMBL4685535 | 0.89 | SMN1; SMN2 (0.48) | MEN1KMT2ATSHRGAANPSR1 | |
| Hydrochloric Acid SCHEMBL4678437 | 0.83 | ABL1 (0.46) | TSHRALDH1A1 | |
| SCHEMBL4678669 | 0.83 | CYP2D6 (0.49) | MEN1KMT2ATSHRGAANPSR1 | |
| Hydrochloric Acid SCHEMBL4683436 | 0.82 | CYP2D6 (0.52) | MEN1KMT2ATSHRGAANPSR1 | |
| Hydrochloric Acid SCHEMBL4679742 | 0.82 | CYP2D6 (0.53) | MEN1KMT2ATSHRGAANPSR1 | |
| Hydrochloric Acid SCHEMBL4678397 | 0.81 | MEN1 (0.50) | MEN1KMT2ATSHRGAANPSR1 | |
| SCHEMBL4683873 | 0.80 | CYP2D6 (0.55) | MEN1KMT2ATSHRGAANPSR1 | |
| Hydrochloric Acid SCHEMBL4679817 | 0.79 | CYP2D6 (0.57) | MEN1KMT2ATSHRGAANPSR1 | |
| Hydrochloric Acid SCHEMBL4682628 | 0.78 | CYP2D6 (0.48) | MEN1KMT2ATSHRGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1058680-B1 | 2-ARYLETHYL-(PIPERIDIN-4-YLMETHYL)AMINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2008-07-09 | — | — | EP | disclosed |
| US-6319920-B1 | MUSCARINIC RECEPTOR ANTAGONIST USED IN GASTROINTESTINAL, GENITOURINARY TRACT, RESPIRATORY TRACT, CARDIOVASCULAR SYSTEM, CENTRAL NERVOUS SYSTEM DISORDERS AND IN ANESTHESIOLOGY AND OPHTHALMOLOGY | SYNTEX (U.S.A.) LLC | 2001-11-20 | — | — | US | disclosed |