SCHEMBL4686299

SCHEMBL4686299

[O]CCCCN1C(=O)CCC[C@@H]1/C=C/C(O)Cc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 19/20 0.71
PTGER2 P43116 2/20 0.71
PTGER3 P43115 2/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4686302 1.00 PTGER4 (0.71) PTGER4PTGER2PTGER3
SCHEMBL4686305 0.93 PTGER4 (0.72) PTGER4PTGER2PTGER3
SCHEMBL14514313 0.91 PTGER4 (0.86) PTGER4PTGER2PTGER3
SCHEMBL4375886 0.90 PTGER4 (0.88) PTGER4PTGER2PTGER3
SCHEMBL4375884 0.90 PTGER4 (0.88) PTGER4PTGER2PTGER3
SCHEMBL12682280 0.90 PTGER4 (0.88) PTGER4PTGER2PTGER3
SCHEMBL14268673 0.90 PTGER4 (0.88) PTGER4PTGER2PTGER3
SCHEMBL1554185 0.90 PTGER4 (0.88) PTGER4PTGER2PTGER3
SCHEMBL4375880 0.90 PTGER4 (0.88) PTGER4PTGER2PTGER3
SCHEMBL4375876 0.90 PTGER4 (0.88) PTGER4PTGER2PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1722795-B1 PIPERIDINYL PROSTAGLANDIN E ANALOGS ALLERGAN INC (US) 2008-05-07 EP claimed