Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 16/20 | 0.54 |
| ▸ | HTR2A | P28223 | 15/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3567218 | 0.85 | SLC6A2 (0.76) | SLC6A2HTR2AHTR6HTR2C | |
| Hydrochloric Acid SCHEMBL3571084 | 0.84 | SLC6A2 (0.74) | SLC6A2HTR2AHTR6HTR2C | |
| SCHEMBL3566398 | 0.83 | SLC6A2 (0.77) | SLC6A2HTR2AHTR6HTR2CPTGER3 | |
| SCHEMBL3581629 | 0.82 | HTR2A (0.77) | SLC6A2HTR2AHTR6HTR2C | |
| SCHEMBL3573795 | 0.82 | SLC6A2 (0.78) | SLC6A2HTR2AHTR6HTR2CPTGER3 | |
| SCHEMBL3576391 | 0.81 | SLC6A2 (0.78) | SLC6A2HTR2AHTR6HTR2CPTGER3 | |
| SCHEMBL3570662 | 0.81 | SLC6A2 (0.64) | SLC6A2HTR2AHTR6HTR2C | |
| SCHEMBL13544626 | 0.81 | SLC6A2 (0.53) | SLC6A2HTR2AHTR6HTR2CPTGER3 | |
| SCHEMBL3560567 | 0.80 | HTR2A (0.78) | SLC6A2HTR2AHTR6HTR2C | |
| SCHEMBL3567790 | 0.80 | SLC6A2 (0.80) | SLC6A2HTR2AHTR6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973876-A2 | SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS | Wyeth (US) | 2008-10-01 | — | — | EP | claimed |
| WO-2007084841-A2 | SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS | WYETH (US) | 2007-07-26 | — | — | WO | claimed |
| EP-1973876-A2 | SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS | Wyeth (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007084841-A2 | SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS | WYETH (US) | 2007-07-26 | — | — | WO | disclosed |