Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HRH2 | P25021 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL4488513 | 0.97 | HRH3 (0.62) | HRH3LMNAMAPTMEN1KMT2A | |
| SCHEMBL4507442 | 0.89 | HRH3 (0.69) | HRH3LMNAMEN1KMT2AMAOB | |
| SCHEMBL4493848 | 0.89 | HRH3 (0.68) | HRH3MAOBHRH2HRH1KDM4E | |
| SCHEMBL4489369 | 0.89 | HRH3 (0.72) | HRH3MAOBHRH2HRH1KDM4E | |
| SCHEMBL4622461 | 0.85 | HRH3 (0.67) | HRH3MAOBHTR2AHRH2HRH1 | |
| Oxalic Acid SCHEMBL4485952 | 0.85 | HRH3 (0.67) | HRH3MAPTMEN1KMT2AMAOB | |
| SCHEMBL4621749 | 0.85 | HRH3 (0.69) | HRH3MAOBHTR2AHRH2HRH1 | |
| SCHEMBL4621772 | 0.85 | HRH3 (0.70) | HRH3MAOBHTR2AHRH2HRH1 | |
| SCHEMBL4621919 | 0.84 | HRH3 (0.66) | HRH3MAOBHRH2HRH1KDM4E | |
| SCHEMBL4620858 | 0.84 | HRH3 (0.69) | HRH3LMNAMAPTMAOBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720544-B1 | NOVEL AZABICYCLIC DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2008-03-19 | — | — | EP | disclosed |