Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 12/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4236549 | 0.96 | MCHR1 (0.42) | MCHR1PKMRAB9ANPC1ALDH1A1 | |
| SCHEMBL4228643 | 0.94 | MCHR1 (0.42) | MCHR1PKMRAB9ANPC1ALDH1A1 | |
| SCHEMBL4228419 | 0.93 | MCHR1 (0.41) | MCHR1PKMRAB9ANPC1ALDH1A1 | |
| SCHEMBL4229361 | 0.92 | MCHR1 (0.42) | MCHR1PKMRAB9ANPC1ALDH1A1 | |
| SCHEMBL4228607 | 0.91 | MCHR1 (0.42) | MCHR1PKMRAB9ANPC1ALDH1A1 | |
| SCHEMBL4229231 | 0.90 | MCHR1 (0.43) | MCHR1PKMRAB9ANPC1ALDH1A1 | |
| SCHEMBL4233531 | 0.89 | MCHR1 (0.44) | MCHR1PKMRAB9ANPC1ALDH1A1 | |
| SCHEMBL4240029 | 0.89 | MCHR1 (0.43) | MCHR1PKMRAB9ANPC1ALDH1A1 | |
| SCHEMBL4238107 | 0.89 | MCHR1 (0.42) | MCHR1PKMRAB9ANPC1ALDH1A1 | |
| SCHEMBL4234121 | 0.88 | MCHR1 (0.41) | MCHR1PKMRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | claimed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | claimed |