Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | AVPR2 | P30518 | 11/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 10/20 | 0.46 |
| ▸ | AVPR1B | P47901 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359772 | 0.85 | AVPR2 (0.56) | KMT2AAVPR2AVPR1AAVPR1BMEN1 | |
| SCHEMBL7354914 | 0.85 | AVPR2 (0.53) | KMT2AAVPR2AVPR1AAVPR1BMEN1 | |
| SCHEMBL4685480 | 0.84 | AVPR2 (0.48) | KMT2AAVPR2AVPR1AAVPR1BMEN1 | |
| SCHEMBL7383926 | 0.84 | AVPR1A (0.49) | KMT2AAVPR2AVPR1AAVPR1BMEN1 | |
| SCHEMBL7357285 | 0.84 | AVPR1A (0.50) | KMT2AAVPR2AVPR1AAVPR1BMEN1 | |
| SCHEMBL4687283 | 0.84 | AVPR2 (0.51) | KMT2AAVPR2AVPR1AAVPR1BMEN1 | |
| SCHEMBL4687327 | 0.83 | AVPR2 (0.55) | KMT2AAVPR2AVPR1AAVPR1BMEN1 | |
| SCHEMBL4685018 | 0.83 | AVPR1A (0.48) | AVPR2AVPR1AAVPR1BTP53 | |
| SCHEMBL8627388 | 0.80 | AVPR2 (0.45) | KMT2AAVPR2AVPR1AMEN1USP2 | |
| SCHEMBL8827696 | 0.74 | AVPR2 (0.49) | AVPR2AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0620003-A1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |