Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.35 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 3/20 | 0.34 |
| ▸ | LAP3 | P28838 | 4/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688315 | 0.81 | CSNK1E (0.45) | F2CSNK1EEPHX1MMP2SLC15A1 | |
| Hydrochloric Acid SCHEMBL5220986 | 0.80 | CSNK1E (0.44) | F2CSNK1EEPHX1MMP2SLC15A1 | |
| SCHEMBL5387047 | 0.79 | CSNK1E (0.46) | F2CSNK1EEPHX1MMP2SLC15A1 | |
| SCHEMBL4693565 | 0.79 | CSNK1E (0.46) | F2CSNK1EEPHX1MMP2SLC15A1 | |
| Hydrochloric Acid SCHEMBL5222515 | 0.78 | CSNK1E (0.45) | F2CSNK1EEPHX1MMP2SLC15A1 | |
| Hydrochloric Acid SCHEMBL5226024 | 0.78 | CSNK1E (0.45) | F2CSNK1EEPHX1MMP2SLC15A1 | |
| SCHEMBL4688261 | 0.77 | CSNK1E (0.50) | F2CSNK1EEPHX1MMP2SLC15A1 | |
| SCHEMBL4689806 | 0.76 | CSNK1E (0.48) | F2CSNK1EEPHX1MMP2SLC15A1 | |
| Hydrochloric Acid SCHEMBL5219524 | 0.76 | CSNK1E (0.49) | F2CSNK1EEPHX1MMP2SLC15A1 | |
| SCHEMBL5390344 | 0.75 | CSNK1E (0.51) | F2CSNK1EEPHX1MMP2SLC15A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107384-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-09-23 | — | — | WO | disclosed |
| EP-1692143-B1 | TRICYCLIC INDOLE HYDROXYETHYLAMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2008-11-12 | — | — | EP | disclosed |