Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4684056 | 1.00 | S1PR1 (0.78) | S1PR1S1PR3 | |
| SCHEMBL4687406 | 0.91 | S1PR1 (0.77) | S1PR1S1PR3 | |
| SCHEMBL4690563 | 0.91 | S1PR1 (0.77) | S1PR1S1PR3 | |
| SCHEMBL1384755 | 0.90 | S1PR1 (0.79) | S1PR1S1PR3 | |
| SCHEMBL4687465 | 0.88 | S1PR1 (1.00) | S1PR1S1PR3 | |
| SCHEMBL4687053 | 0.87 | S1PR1 (0.82) | S1PR1S1PR3 | |
| SCHEMBL4687130 | 0.86 | S1PR1 (0.79) | S1PR1S1PR3 | |
| SCHEMBL4689385 | 0.86 | S1PR1 (0.79) | S1PR1S1PR3 | |
| SCHEMBL2949102 | 0.85 | S1PR1 (0.77) | S1PR1S1PR3 | |
| SCHEMBL2944348 | 0.85 | S1PR1 (0.77) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805163-B1 | 1,1A,5,5A-TETRAHYDRO-3-THIA-CYCLOPROPA[A]PENTALENES: TRICYCLIC THIOPHENE DERIVATIVES AS S1P1/EDG1 RECEPTOR AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2008-10-01 | — | — | EP | disclosed |