Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 6/20 | 0.48 |
| ▸ | HTR6 | P50406 | 5/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | HTR1E | P28566 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4123596 | 0.99 | HRH1 (0.48) | HRH1HTR6ADRA2AHTR2AHTR2C | |
| SCHEMBL3714047 | 0.86 | HRH1 (0.44) | HRH1HTR6ADRA2AHTR2AHTR2C | |
| SCHEMBL3625976 | 0.82 | KDM4E (0.69) | HRH1HTR6ADRA2AHTR2AHTR2C | |
| SCHEMBL168938 | 0.81 | HRH1 (0.70) | HRH1HTR6ADRA2AHTR2AHTR2C | |
| SCHEMBL3714001 | 0.81 | KDM4E (0.46) | HRH1HTR6ADRA2AHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL2835754 | 0.80 | HRH1 (0.68) | HRH1HTR6ADRA2AHTR2AHTR2C | |
| SCHEMBL13696305 | 0.80 | HRH1 (0.56) | HRH1HTR6ADRA2AHTR2AHTR2C | |
| SCHEMBL3715511 | 0.77 | HRH1 (0.53) | HRH1HTR6ADRA2AHTR2AHTR2C | |
| SCHEMBL13654434 | 0.75 | HRH1 (0.67) | HRH1HTR6ADRA2AHTR2AHTR2C | |
| SCHEMBL13696232 | 0.72 | KDM4E (0.69) | HRH1HTR6ADRA2AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692131-A4 | METHODS AND COMPOSITIONS FOR SLOWING AGING | MEDIVATION INC (US) | 2008-08-20 | — | — | EP | claimed |
| EP-1692131-A2 | METHODS AND COMPOSITIONS FOR SLOWING AGING | MEDIVATION, INC. (US) | 2006-08-23 | — | — | EP | claimed |
| WO-2005055951-A2 | METHODS AND COMPOSITIONS FOR SLOWING AGING | MEDIVATION, INC. (US) | 2005-06-23 | — | — | WO | claimed |