SCHEMBL468997

SCHEMBL468997

CN(C)C(CN)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 1/20 0.55
HTR2A P28223 5/20 0.52
TAAR1 Q96RJ0 4/20 0.52
HRH1 P35367 4/20 0.46
CHRNB2 P17787 2/20 0.46
CHRNA4 P43681 2/20 0.46
CHRNB4 P30926 1/20 0.46
CHRNA3 P32297 1/20 0.46
SLC6A2 P23975 2/20 0.46
SLC6A4 P31645 2/20 0.46
AOC3 Q16853 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
SLC6A3 Q01959 1/20 0.44
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL16227265 0.98 NISCH (0.53) NISCHHTR2ATAAR1HRH1CHRNB2
SCHEMBL22364526 0.83 CHRNA7 (0.54) NISCHHTR2ATAAR1CHRNB2CHRNA4
SCHEMBL3716302 0.83 HRH1 (0.56) NISCHHTR2ATAAR1HRH1CHRNB2
SCHEMBL1443955 0.79 HRH1 (0.59) NISCHHTR2ATAAR1HRH1CHRNB2
SCHEMBL8926699 0.79 HTR2A (0.48) HTR2AHRH1CHRNB2CHRNA4CHRNB4
SCHEMBL119104 0.79 HTR2A (0.48) HTR2AHRH1CHRNB2CHRNA4CHRNB4
SCHEMBL171013 0.79 HTR2A (0.48) HTR2AHRH1CHRNB2CHRNA4CHRNB4
SCHEMBL19376998 0.78 NISCH (0.52) NISCHSLC6A4AOC3SLC6A3
SCHEMBL31016671 0.78 AOC3 (0.47) NISCHTAAR1SLC6A2SLC6A4AOC3
SCHEMBL29144175 0.78 TAAR1 (0.54) NISCHHTR2ATAAR1HRH1CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118791728-A Clay stabilizer and preparation method thereof 中石化西南石油工程有限公司 2024-10-18 CN claimed
WO-2016087603-A1 PROCESS FOR PREPARING A MODIFIED NATURAL RUBBER BY MEANS OF A MODIFIER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2016-06-09 WO claimed
EP-2547656-B1 PYRIDINE AND PYRAZINE DERIVATIVE FOR THE TREATMENT OF CF NOVARTIS AG (CH) 2015-09-30 EP claimed
EP-2845593-A1 Pyridine and pyrazine derivative for the treatment of chronic obstructive pulmonary disease Novartis AG (CH) 2015-03-11 EP claimed
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 US disclosed
CN-119775151-A Clay stabilizer and preparation method thereof 中石化西南石油工程有限公司 2025-04-08 CN disclosed
CN-119775152-A Clay stabilizer and preparation method thereof 中石化西南石油工程有限公司 2025-04-08 CN disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 US disclosed
CN-118791728-B Clay stabilizer and preparation method thereof 中石化西南石油工程有限公司 2025-01-24 CN disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 EP disclosed
CN-118791728-A Clay stabilizer and preparation method thereof 中石化西南石油工程有限公司 2024-10-18 CN disclosed
WO-2005100305-A1 ANDROGEN MODULATORS WARNER-LAMBERT COMPANY LLC (US) 2005-10-27 WO disclosed
WO-2005095343-A1 DPP-IV INHIBITORS SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) 2005-10-13 WO disclosed
EP-0139661-A1 SECONDARY AMINES BEECHAM GROUP PLC (GB) 1985-05-08 EP disclosed
WO-1984003278-A1 SECONDARY AMINES BEECHAM GROUP PLC (GB) 1984-08-30 WO disclosed
US-4374779-A Nitrosoamino-actonitriles AMERICAN HOME PRODUCTS CORPORATION (US) 1983-02-22 US disclosed
WO-1982001184-A1 SYDNONE IMINE DERIVATIVES,INTERMEDIATES THEREFORE AND METHODS OF PREPARATION AMERICAN HOME PROD (US) 1982-04-15 WO disclosed
US-4324897-A 1,2,3 Oxadiazolium salts AMERICAN HOME PRODUCTS CORPORATION (US) 1982-04-13 US disclosed
US-4289885-A 3-[2-(Dimethylamino)-2-phenylethyl]N-[phenylamino)carbonyl]sydnone imine, a new central nervous system stimulant AMERICAN HOME PRODUCTS CORPORATION (US) 1981-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 NISCH 4235/4885HTR2A 4383/4885TAAR1 4805/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 NISCH 4235/4885HTR2A 4383/4885TAAR1 4805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.