Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 15/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 12/20 | 0.50 |
| ▸ | KDR | P35968 | 12/20 | 0.50 |
| ▸ | FLT1 | P17948 | 6/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3384431 | 1.00 | FGFR1 (0.50) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL4690001 | 1.00 | FGFR1 (0.50) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL3380133 | 0.79 | CHEK1 (0.63) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL15910628 | 0.77 | FGFR1 (0.70) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL3381617 | 0.76 | PDGFRB (0.51) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL5352535 | 0.75 | FGFR1 (0.53) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL27677279 | 0.75 | PDGFRB (0.53) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL3381523 | 0.72 | FGFR1 (0.61) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL7532191 | 0.70 | PDGFRB (0.57) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL3383676 | 0.70 | FGFR1 (0.58) | FGFR1PDGFRBKDRFLT1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650203-B1 | Process of preparation of benzimidazol-2-yl quinolinone derivatives | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2008-02-20 | — | — | EP | disclosed |