SCHEMBL4690362

SCHEMBL4690362

N=C1CCCN1c1ccc(NC(=O)Cc2ccc3nc(-c4ccc(Cl)s4)[nH]c3c2)cc1

nearest known ligand 0.84

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 20/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3861343 0.94 F10 (0.74) F10
SCHEMBL3868937 0.92 F10 (0.74) F10
SCHEMBL3866098 0.85 F10 (0.88) F10
SCHEMBL3866715 0.83 F10 (0.88) F10
SCHEMBL3867568 0.82 F10 (0.63) F10
SCHEMBL3864987 0.80 F10 (0.54) F10
SCHEMBL3864251 0.77 F10 (0.88) F10
SCHEMBL3862457 0.76 F10 (0.53) F10
SCHEMBL3871409 0.75 F10 (0.71) F10
SCHEMBL3865235 0.74 F10 (0.72) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1558247-B1 BENZIMIDAZOLE DERIVATIVES MERCK PATENT GMBH (DE) 2008-02-20 — — EP disclosed
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