Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.75 |
| ▸ | F2 | P00734 | 4/20 | 0.75 |
| ▸ | F11 | P03951 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4690422 | 1.00 | F10 (0.75) | F10F2F11 | |
| SCHEMBL5631572 | 0.91 | F10 (0.70) | F10F2F11 | |
| SCHEMBL5434026 | 0.91 | F10 (0.70) | F10F2F11 | |
| SCHEMBL5432864 | 0.91 | F10 (0.71) | F10F2F11 | |
| SCHEMBL5432609 | 0.90 | F10 (0.79) | F10F2F11 | |
| SCHEMBL5442385 | 0.89 | F10 (0.75) | F10F2F11 | |
| SCHEMBL5631313 | 0.89 | F10 (0.74) | F10F2F11 | |
| SCHEMBL5433022 | 0.89 | F10 (0.74) | F10F2F11 | |
| SCHEMBL5633444 | 0.89 | F10 (0.74) | F10F2F11 | |
| SCHEMBL5629967 | 0.86 | F10 (0.76) | F10F2F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205318-B2 | Lactam-containing cyclic diamines and derivatives as a factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-17 | — | — | US | claimed |
| EP-1603572-A4 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-06-25 | — | — | EP | disclosed |
| US-7205318-B2 | Lactam-containing cyclic diamines and derivatives as a factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-17 | — | — | US | disclosed |
| EP-1603572-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Company (US) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004082687-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |