Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3840540 | 0.78 | SLC6A4 (0.58) | TAAR1SLC6A4SLC6A2SIGMAR1MAOA | |
| SCHEMBL27284505 | 0.78 | SLC6A4 (0.58) | TAAR1SLC6A4SLC6A2SIGMAR1MAOA | |
| Levamfetamine SCHEMBL573666 | 0.78 | SLC6A2 (0.95) | TAAR1SLC6A4SLC6A2SIGMAR1MAOA | |
| Levamfetamine SCHEMBL4070216 | 0.78 | SLC6A2 (0.95) | TAAR1SLC6A4SLC6A2SIGMAR1MAOA | |
| Amphetamine SCHEMBL27581784 | 0.78 | SLC6A2 (0.95) | TAAR1SLC6A4SLC6A2SIGMAR1MAOA | |
| Amphetamine SCHEMBL4070210 | 0.78 | SLC6A2 (0.95) | TAAR1SLC6A4SLC6A2SIGMAR1MAOA | |
| Dextroamphetamine SCHEMBL1042914 | 0.78 | SLC6A2 (0.95) | TAAR1SLC6A4SLC6A2SIGMAR1MAOA | |
| Amphetamine SCHEMBL573665 | 0.78 | SLC6A2 (0.95) | TAAR1SLC6A4SLC6A2SIGMAR1MAOA | |
| Dextroamphetamine SCHEMBL9114306 | 0.78 | SLC6A2 (0.95) | TAAR1SLC6A4SLC6A2SIGMAR1MAOA | |
| SCHEMBL3840804 | 0.75 | SLC6A4 (0.54) | TAAR1SLC6A4SLC6A2SIGMAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1375489-B1 | MEDICINAL COMPOSITION CONTAINING 1,3-THIAZINE DERIVATIVE | SHIONOGI & CO (JP) | 2008-08-20 | — | — | EP | disclosed |
| US-6916806-B2 | Medicinal composition containing 1,3-thiazine derivative | SHIONOGI & CO., LTD. (JP) | 2005-07-12 | — | — | US | disclosed |
| US-20040116326-A1 | Medicinal composition containing 1,3-thiazine derivative | SHIONOGI & CO., LTD. (JP) | 2004-06-17 | — | — | US | disclosed |
| EP-1375489-A1 | MEDICINAL COMPOSITION CONTAINING 1,3-THIAZINE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2004-01-02 | — | — | EP | disclosed |