Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688469 | 0.82 | CCR6 (0.47) | CCR6NOS2NOS3NOS1KDM1A | |
| SCHEMBL4689885 | 0.79 | CCR6 (0.44) | CCR6NOS2NOS3NOS1KDM1A | |
| SCHEMBL13980741 | 0.79 | CCR6 (0.46) | CCR6NOS2NOS3NOS1KDM1A | |
| SCHEMBL13980613 | 0.78 | CCR6 (0.44) | CCR6NOS2NOS3NOS1KDM1A | |
| SCHEMBL4688008 | 0.78 | CCR6 (0.41) | CCR6SIGMAR1NOS2NOS3NOS1 | |
| SCHEMBL4786444 | 0.78 | RECQL (0.40) | CCR6NOS2MEN1KMT2AALDH1A1 | |
| SCHEMBL4687972 | 0.78 | CCR6 (0.42) | CCR6NOS2NOS3NOS1KDM1A | |
| SCHEMBL13980739 | 0.78 | CCR6 (0.47) | CCR6NOS2NOS3NOS1KDM1A | |
| SCHEMBL4690523 | 0.77 | CCR6 (0.45) | CCR6NOS2NOS3NOS1KDM1A | |
| SCHEMBL4692641 | 0.77 | CCR6 (0.41) | CCR6NOS2NOS3NOS1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443046-B1 | NOVEL 4-(2FUROYL)AMINOPIPERIDINES, INTERMEDIATES IN SYNTHESIZING THE SAME, PROCESS FOR PRODUCING THE SAME AND MEDICINAL USE OF THE SAME | KYORIN SEIYAKU KK (JP) | 2008-12-17 | — | — | EP | disclosed |