Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.64 |
| ▸ | F2RL3 | Q96RI0 | 14/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2943235 | 0.81 | MKNK1 (0.67) | MKNK1F2RL3FYN | |
| SCHEMBL2947501 | 0.79 | MKNK1 (0.51) | MKNK1F2RL3FYN | |
| SCHEMBL2950873 | 0.79 | MKNK1 (0.64) | MKNK1F2RL3FYN | |
| SCHEMBL4595119 | 0.79 | MKNK1 (0.56) | MKNK1F2RL3 | |
| SCHEMBL2948001 | 0.78 | MKNK1 (1.00) | MKNK1FYN | |
| SCHEMBL2940434 | 0.78 | MKNK1 (0.54) | MKNK1F2RL3FYN | |
| SCHEMBL4595114 | 0.74 | MKNK1 (0.50) | MKNK1F2RL3 | |
| SCHEMBL2948003 | 0.73 | MKNK1 (0.55) | MKNK1F2RL3FYN | |
| SCHEMBL3869345 | 0.71 | F2RL3 (0.49) | MKNK1F2RL3 | |
| SCHEMBL4326841 | 0.70 | PIM1 (0.67) | MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1900739-A1 | Diazolodiazine derivatives as kinase inhibitors | CELLZOME AG (DE) | 2008-03-19 | — | — | EP | claimed |
| WO-2008025822-A1 | DIAZOLODIAZINE DERIVATIVES AS KINASE INHIBITORS | CELLZOME LIMITED (GB) | 2008-03-06 | — | — | WO | claimed |
| EP-1900739-A1 | Diazolodiazine derivatives as kinase inhibitors | CELLZOME AG (DE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2008025822-A1 | DIAZOLODIAZINE DERIVATIVES AS KINASE INHIBITORS | CELLZOME LIMITED (GB) | 2008-03-06 | — | — | WO | disclosed |