SCHEMBL469143

SCHEMBL469143

CCCCCc1c[nH]cn1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.44
HRH3 Q9Y5N1 3/20 0.37
HRH4 Q9H3N8 2/20 0.37
LPL P06858 3/20 0.33
LIPG Q9Y5X9 3/20 0.33
PAK1 Q13153 1/20 0.33
PDPK1 O15530 1/20 0.33
TLR7 Q9NYK1 1/20 0.33
PI4KA P42356 1/20 0.33
PI4K2B Q8TCG2 1/20 0.33
PI4K2A Q9BTU6 1/20 0.33
PI4KB Q9UBF8 1/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
IDO1 P14902 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL675808 0.98 KCNH2 (0.47) KCNH2HRH3HRH4LPLLIPG
SCHEMBL28061446 0.98 KCNH2 (0.47) KCNH2HRH3HRH4LPLLIPG
SCHEMBL31554343 0.98 KCNH2 (0.47) KCNH2HRH3HRH4LPLLIPG
SCHEMBL2696234 0.98 KCNH2 (0.47) KCNH2HRH3HRH4LPLLIPG
SCHEMBL2696007 0.98 KCNH2 (0.47) KCNH2HRH3HRH4LPLLIPG
SCHEMBL2695561 0.98 KCNH2 (0.47) KCNH2HRH3HRH4LPLLIPG
SCHEMBL2697514 0.98 KCNH2 (0.47) KCNH2HRH3HRH4LPLLIPG
SCHEMBL2697904 0.98 KCNH2 (0.47) KCNH2HRH3HRH4LPLLIPG
SCHEMBL674217 0.98 KCNH2 (0.47) KCNH2HRH3HRH4LPLLIPG
SCHEMBL360634 0.98 KCNH2 (0.47) KCNH2HRH3HRH4LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024110575-A1 OLIGOMERISATION OF ALCOHOLS Terra Mater BV (BE) 2024-05-30 WO claimed
CN-101431994-A Use of CBx cannabinoid receptor modulators as potassium channel modulators SOLVAY PHARM GMBH (DE) 2009-05-13 CN claimed
CN-101431998-A Containing CBxPharmaceutical compositions of cannabinoid receptor modulators and potassium channel modulators SOLVAY PHARM GMBH (DE) 2009-05-13 CN claimed
US-5462959-A 4-aryl-imidazole derivatives AKZO N.V. (NL) 1995-10-31 US claimed
WO-2024110575-A1 OLIGOMERISATION OF ALCOHOLS Terra Mater BV (BE) 2024-05-30 WO disclosed
EP-4066834-A1 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF PI3K-GAMMA MEDIATED DISORDERS Infinity Pharmaceuticals, Inc. (US) 2022-10-05 EP disclosed
EP-1844020-B1 HETEROCYCLIC CARBOXAMIDE COMPOUNDS AS STEROID NUCLEAR RECEPTOR LIGANDS EXELIXIS INC (US) 2017-09-06 EP disclosed
US-9551812-B2 Adhesive composition, adhesive layer, optical member, and adhesive sheet CHEIL INDUSTRIES, INC. (KR) 2017-01-24 US disclosed
US-9315691-B2 Adhesive composition CHEIL INDUSTRIES, INC. (KR) 2016-04-19 US disclosed
US-9290503-B2 Tricyclic compound derivatives useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders CHEMBRIDGE CORPORATION (US) 2016-03-22 US disclosed
US-9273055-B2 Tyrosine kinase inhibitors CHEMBRIDGE CORPORATION (US) 2016-03-01 US disclosed
US-9249147-B2 Tyrosine kinase inhibitors CHEMBRIDGE CORPORATION (US) 2016-02-02 US disclosed
US-5462959-A 4-aryl-imidazole derivatives AKZO N.V. (NL) 1995-10-31 US disclosed
CN-1106982-A Maillard reaction inhibitor OTSUKA PHARMA CO LTD (JP) 1995-08-16 CN disclosed
EP-0392160-A1 Azole-1-alkanamides as antiarrhythmic agents and preparation thereof STERLING DRUG INC. (US) 1990-10-17 EP disclosed
US-4962120-A ANTIARRHYTHMIA AGENTS STERLING DRUG INC. (US) 1990-10-09 US disclosed
EP-0271586-A1 $g(b)-LACTAM COMPOUNDS AND PROCESS FOR THEIR PREPARATION SAGAMI CHEMICAL RESEARCH CENTER (JP) 1988-06-22 EP disclosed
EP-0106962-A1 Process for preparing 4(or 5)-(1-hydroxyalkyl) imidazoles AMERICAN CYANAMID COMPANY (US) 1984-05-02 EP disclosed
US-4069035-A PLANT GROWTH REGULATORS, PICRATE DYES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-01-17 US disclosed
US-4038285-A BUFFER SOLUTIONS, PICRATE DYES, PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-07-26 US disclosed