SCHEMBL4691672

SCHEMBL4691672

CC(=O)c1ccc(-c2ccc(OCc3cc(OC(=O)O)oc3C)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 16/20 0.72
MAOB P27338 4/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4689374 0.90 PTGER4 (0.59) PTGER4
SCHEMBL4693788 0.89 PTGER4 (0.70) PTGER4
SCHEMBL4694643 0.88 PTGER4 (0.58) PTGER4
SCHEMBL4692290 0.88 PTGER4 (0.71) PTGER4
SCHEMBL4693554 0.86 PTGER4 (0.72) PTGER4
SCHEMBL4693688 0.86 PTGER4 (0.57) PTGER4
SCHEMBL4687914 0.85 PTGER4 (0.74) PTGER4
SCHEMBL4693795 0.84 PTGER4 (0.55) PTGER4
SCHEMBL4690414 0.84 PTGER4 (0.55) PTGER4
SCHEMBL4687523 0.84 PTGER4 (0.55) PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1603893-B1 EP4 RECEPTOR ANTAGONISTS ASTERAND UK LTD (GB) 2008-05-21 EP claimed