Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 17/20 | 0.57 |
| ▸ | CNR2 | P34972 | 10/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4687817 | 0.92 | CNR1 (0.54) | CNR1CNR2 | |
| SCHEMBL4691738 | 0.92 | CNR1 (0.60) | CNR1CNR2 | |
| SCHEMBL4690861 | 0.90 | CNR1 (0.63) | CNR1CNR2USP2ALDH1A1POLB | |
| SCHEMBL4691613 | 0.89 | CNR1 (0.62) | CNR1CNR2USP2ALDH1A1POLB | |
| SCHEMBL2653467 | 0.89 | CNR1 (0.62) | CNR1CNR2USP2ALDH1A1POLB | |
| SCHEMBL2652057 | 0.87 | CNR1 (0.62) | CNR1CNR2 | |
| SCHEMBL4688987 | 0.87 | CNR1 (0.63) | CNR1CNR2USP2ALDH1A1POLB | |
| SCHEMBL4688183 | 0.86 | CNR1 (0.51) | CNR1CNR2USP2ALDH1A1POLB | |
| SCHEMBL4688836 | 0.86 | CNR1 (0.60) | CNR1CNR2 | |
| SCHEMBL4692613 | 0.85 | CNR1 (0.58) | CNR1CNR2USP2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496838-A4 | SUBSTITUTED AMIDES | MERCK & CO INC (US) | 2008-07-02 | — | — | EP | claimed |
| EP-1496838-A2 | SUBSTITUTED AMIDES | Merck & Co., Inc. (US) | 2005-01-19 | — | — | EP | claimed |
| WO-2003077847-A2 | SUBSTITUTED AMIDES | MERCK & CO., INC. (US) | 2003-09-25 | — | — | WO | claimed |
| EP-1496838-A4 | SUBSTITUTED AMIDES | MERCK & CO INC (US) | 2008-07-02 | — | — | EP | disclosed |
| EP-1496838-A2 | SUBSTITUTED AMIDES | Merck & Co., Inc. (US) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003077847-A2 | SUBSTITUTED AMIDES | MERCK & CO., INC. (US) | 2003-09-25 | — | — | WO | disclosed |