Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.56 |
| ▸ | PPARA | Q07869 | 12/20 | 0.56 |
| ▸ | PPARD | Q03181 | 10/20 | 0.56 |
| ▸ | PHGDH | O43175 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2806181 | 0.85 | PPARG (0.75) | PPARGPPARAPPARD | |
| SCHEMBL4694981 | 0.82 | PPARG (0.64) | PPARGPPARAPPARDPHGDH | |
| SCHEMBL4689976 | 0.78 | PPARG (0.71) | PPARGPPARAPPARDPHGDHALDH1A1 | |
| SCHEMBL4689487 | 0.73 | PPARG (0.76) | PPARGPPARAPPARDPHGDH | |
| SCHEMBL14144726 | 0.73 | PPARG (0.82) | PPARGPPARAPPARD | |
| SCHEMBL4692544 | 0.72 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL2807974 | 0.72 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL2859210 | 0.71 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL4692259 | 0.71 | PPARG (0.85) | PPARGPPARAPPARD | |
| SCHEMBL4695139 | 0.71 | PPARG (0.85) | PPARGPPARAPPARDPHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685113-B1 | SUBSTITUTED PYRAZOLES AS PPAR AGONISTS | SMITHKLINE BEECHAM CORP (US) | 2008-07-30 | — | — | EP | claimed |