SCHEMBL46935

SCHEMBL46935

CCc1cccc(C(=O)O)c1

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.66
FOLH1 Q04609 3/20 0.66
MRGPRX4 Q96LA9 5/20 0.58
TP53 P04637 2/20 0.58
PKM P14618 2/20 0.58
NFKB1 P19838 2/20 0.58
NFKB2 Q00653 2/20 0.58
RELA Q04206 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
ALDH1A1 P00352 1/20 0.57
RAB9A P51151 1/20 0.54
RXFP1 Q9HBX9 1/20 0.54
HTT P42858 1/20 0.54
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
HIF1A Q16665 1/20 0.53
ANPEP P15144 1/20 0.53
ENPEP Q07075 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30394310 1.00 BCL2 (0.66) BCL2FOLH1MRGPRX4TP53PKM
SCHEMBL6909307 0.98 BCL2 (0.64) BCL2FOLH1MRGPRX4TP53PKM
SCHEMBL6909306 0.98 BCL2 (0.64) BCL2FOLH1MRGPRX4TP53PKM
SCHEMBL6918575 0.98 BCL2 (0.64) BCL2FOLH1MRGPRX4TP53PKM
SCHEMBL6917284 0.98 BCL2 (0.64) BCL2FOLH1MRGPRX4TP53PKM
SCHEMBL6916420 0.98 BCL2 (0.64) BCL2FOLH1MRGPRX4TP53PKM
SCHEMBL27852733 0.98 BCL2 (0.64) BCL2FOLH1MRGPRX4TP53PKM
SCHEMBL6916326 0.98 BCL2 (0.64) BCL2FOLH1MRGPRX4TP53PKM
Ammonia Solution, Strong SCHEMBL22042022 0.98 BCL2 (0.64) BCL2FOLH1MRGPRX4TP53PKM
SCHEMBL6909354 0.98 BCL2 (0.64) BCL2FOLH1MRGPRX4TP53PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 825 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119638770-A Clobetasol propionate derivative and preparation method thereof 复旦大学 2025-03-18 CN claimed
CN-109762292-A A kind of ABS composition and a kind of preparation method of ABS composition 金发科技股份有限公司 2019-05-17 CN claimed
CN-109517328-A A kind of ABS composition and a kind of preparation method of ABS composition 金发科技股份有限公司 2019-03-26 CN claimed
US-20190002447-A1 BIFUNCTIONAL MOLECULES WITH ANTIBODY-RECRUITING AND ENTRY INHIBITORY ACTIVITY AGAINST THE HUMAN IMMUNODEFICIENCY VIRUS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2019-01-03 US claimed
US-20180348188-A1 METHOD OF USING BIOMOLECULES TO PREDICT SOURING IN OILFIELD SYSTEMS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-12-06 US claimed
CN-106699755-B A kind of aza-acridine class compound and preparation method thereof and purposes 清华大学深圳研究生院 2018-09-21 CN claimed
CN-108341902-A Catalytic component for vinyl polymerization and preparation method thereof and catalyst for vinyl polymerization 中国石油化工股份有限公司 2018-07-31 CN claimed
CN-108341901-A Catalytic component for vinyl polymerization and preparation method thereof and catalyst for vinyl polymerization 中国石油化工股份有限公司 2018-07-31 CN claimed
CN-105524058-B Pyrazolo [1,5 a] pyridine compounds and their and its application 广州艾格生物科技有限公司 2018-03-27 CN claimed
US-20170253582-A1 TRIAZOLE MODIFIED COUMARIN AND BIPHENYL AMIDE-BASED HSP90 INHIBITORS REATA PHARMACEUTICALS, INC. 2017-09-07 US claimed
CN-1894818-A Fuel for fuel cell, fuel cell and use thereof KURITA WATER IND LTD (JP) 2007-01-10 CN claimed
US-20060283469-A1 Tobacco with an increased level of natural tar diluents PHILIP MORRIS USA INC. (US) 2006-12-21 US claimed
CN-1694874-A Benzodiazepine * derivatives and pharmaceutical compositions containing them ARROW THERAPEUTICS LTD (GB) 2005-11-09 CN claimed
CN-1659174-A Hydrogen storage method, hydrogen clathrate and process for producing the same KURITA WATER IND LTD (JP) 2005-08-24 CN claimed
CN-1604950-A Glycerin triester plasticizer FERRO CORP (US) 2005-04-06 CN claimed
EP-1456322-A4 GLYCERIN TRIESTER PLASTICIZER FERRO CORP (US) 2005-03-16 EP claimed
EP-1456322-A1 GLYCERIN TRIESTER PLASTICIZER FERRO CORPORATION (US) 2004-09-15 EP claimed
WO-2003054106-A1 GLYCERIN TRIESTER PLASTICIZER FERRO CORPORATION (US) 2003-07-03 WO claimed
US-20030116750-A1 Glycerin triester plasticizer POLYMER ADDITIVES, INC. 2003-06-26 US claimed
EP-0249999-A2 Triazolyl ethyl ethers and fungicides containing them BASF Aktiengesellschaft (DE) 1987-12-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190002447-A1 BIFUNCTIONAL MOLECULES WITH ANTIBODY-RECRUITING AND ENTRY INHIBITORY ACTIVITY AGAINST THE HUMAN IMMUNODEFICIENCY VIRUS CD4, HAVCR2, CD2 BCL2 1102/4885FOLH1 1506/4885MRGPRX4 2182/4885
US-20170253582-A1 TRIAZOLE MODIFIED COUMARIN AND BIPHENYL AMIDE-BASED HSP90 INHIBITORS HSP90AB1, HSP90AB2P, HSP90AA1 BCL2 1189/4885FOLH1 3034/4885MRGPRX4 3751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.