Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 18/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3535664 | 0.86 | PTGER4 (0.73) | PTGER4 | |
| SCHEMBL4693788 | 0.85 | PTGER4 (0.70) | PTGER4 | |
| SCHEMBL4688346 | 0.85 | PTGER4 (0.55) | PTGER4MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL4687807 | 0.84 | PTGER4 (0.75) | PTGER4FFAR1FFAR4 | |
| SCHEMBL4687523 | 0.83 | PTGER4 (0.55) | PTGER4FFAR1FFAR4 | |
| SCHEMBL4693615 | 0.82 | PTGER4 (0.53) | PTGER4FFAR1FFAR4 | |
| SCHEMBL4692162 | 0.81 | PTGER4 (0.58) | PTGER4FFAR1FFAR4MEN1ALDH1A1 | |
| SCHEMBL4687914 | 0.80 | PTGER4 (0.74) | PTGER4 | |
| SCHEMBL4694643 | 0.79 | PTGER4 (0.58) | PTGER4 | |
| SCHEMBL4692290 | 0.79 | PTGER4 (0.71) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603893-B1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LTD (GB) | 2008-05-21 | — | — | EP | claimed |