Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | AOC2 | O75106 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL469278 | 0.84 | CNR2 (0.38) | CNR2CNR1 | |
| SCHEMBL10147821 | 0.81 | CNR2 (0.40) | CNR2CNR1 | |
| SCHEMBL10146087 | 0.78 | CNR2 (0.39) | CNR2CNR1 | |
| SCHEMBL18638816 | 0.78 | CNR2 (0.39) | CNR2CNR1 | |
| SCHEMBL12289489 | 0.76 | CNR2 (0.46) | CNR2CNR1AOC2MAOA | |
| SCHEMBL13413804 | 0.75 | CNR2 (0.40) | CNR2CNR1 | |
| SCHEMBL10177092 | 0.75 | CNR2 (0.43) | CNR2CNR1AOC2MAOA | |
| SCHEMBL10098834 | 0.74 | CNR2 (0.35) | CNR2CNR1 | |
| SCHEMBL766752 | 0.74 | CNR2 (0.47) | CNR2CNR1 | |
| SCHEMBL13448691 | 0.74 | CNR2 (0.32) | CNR2CNR1AOC2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012307-A9 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-03-15 | — | — | WO | disclosed |
| WO-2012012307-A1 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-26 | — | — | WO | disclosed |