Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 13/20 | 0.63 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.53 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4695095 | 0.82 | FYN (0.67) | FYNIKBKB | |
| SCHEMBL15254599 | 0.81 | MKNK1 (0.57) | FYNMKNK1IKBKB | |
| SCHEMBL19467148 | 0.81 | FYN (0.62) | FYNMKNK1IKBKBPIM1 | |
| SCHEMBL19467246 | 0.81 | IKBKB (0.52) | FYNMKNK1IKBKBPIM1PIM2 | |
| SCHEMBL4692424 | 0.80 | FYN (0.64) | FYNMKNK1IKBKB | |
| SCHEMBL15254184 | 0.80 | FYN (0.55) | FYNMKNK1IKBKBPIM1 | |
| SCHEMBL15254545 | 0.79 | IKBKB (0.53) | FYNMKNK1IKBKB | |
| SCHEMBL15254759 | 0.79 | IKBKB (0.53) | FYNMKNK1IKBKB | |
| Hydrochloric Acid SCHEMBL3453044 | 0.79 | FYN (0.84) | FYNMKNK1PIM1 | |
| SCHEMBL19466949 | 0.78 | IKBKB (0.55) | FYNMKNK1IKBKBPIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1900739-A1 | Diazolodiazine derivatives as kinase inhibitors | CELLZOME AG (DE) | 2008-03-19 | — | — | EP | claimed |
| EP-1900739-A1 | Diazolodiazine derivatives as kinase inhibitors | CELLZOME AG (DE) | 2008-03-19 | — | — | EP | disclosed |