Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 17/20 | 0.58 |
| ▸ | CNR2 | P34972 | 10/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4692569 | 0.95 | CNR1 (0.53) | CNR1CNR2 | |
| SCHEMBL4691557 | 0.94 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL4687849 | 0.94 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL4692000 | 0.94 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL4694395 | 0.94 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL4691059 | 0.89 | CNR1 (0.64) | CNR1CNR2 | |
| SCHEMBL4692540 | 0.89 | CNR1 (0.64) | CNR1CNR2 | |
| SCHEMBL4687817 | 0.88 | CNR1 (0.54) | CNR1CNR2 | |
| SCHEMBL4690861 | 0.88 | CNR1 (0.63) | CNR1CNR2 | |
| SCHEMBL4691613 | 0.87 | CNR1 (0.62) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496838-A4 | SUBSTITUTED AMIDES | MERCK & CO INC (US) | 2008-07-02 | — | — | EP | claimed |
| EP-1496838-A2 | SUBSTITUTED AMIDES | Merck & Co., Inc. (US) | 2005-01-19 | — | — | EP | claimed |
| WO-2003077847-A2 | SUBSTITUTED AMIDES | MERCK & CO., INC. (US) | 2003-09-25 | — | — | WO | claimed |
| EP-1496838-A4 | SUBSTITUTED AMIDES | MERCK & CO INC (US) | 2008-07-02 | — | — | EP | disclosed |
| EP-1496838-A2 | SUBSTITUTED AMIDES | Merck & Co., Inc. (US) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003077847-A2 | SUBSTITUTED AMIDES | MERCK & CO., INC. (US) | 2003-09-25 | — | — | WO | disclosed |