Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 15/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3537246 | 0.77 | PTGER4 (0.66) | PTGER4 | |
| SCHEMBL3537242 | 0.77 | PTGER4 (0.66) | PTGER4 | |
| SCHEMBL3531764 | 0.69 | PTGER4 (0.55) | PTGER4 | |
| SCHEMBL3536176 | 0.69 | PTGER4 (0.67) | PTGER4 | |
| SCHEMBL3536178 | 0.69 | PTGER4 (0.67) | PTGER4 | |
| SCHEMBL8173827 | 0.69 | KDM4E (0.73) | PTGER4KDM4ESMN1; SMN2 | |
| SCHEMBL8173830 | 0.69 | KDM4E (0.73) | PTGER4KDM4ESMN1; SMN2 | |
| SCHEMBL1756460 | 0.69 | PTGER4 (1.00) | PTGER4 | |
| SCHEMBL4693788 | 0.68 | PTGER4 (0.70) | PTGER4 | |
| SCHEMBL1161220 | 0.67 | KDM4E (0.74) | PTGER4KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603893-B1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LTD (GB) | 2008-05-21 | — | — | EP | claimed |